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    EIF1 eukaryotic translation initiation factor 1 [ Homo sapiens (human) ]

    Gene ID: 10209, updated on 14-Jun-2016
    Official Symbol
    EIF1provided by HGNC
    Official Full Name
    eukaryotic translation initiation factor 1provided by HGNC
    Primary source
    HGNC:HGNC:3249
    See related
    Ensembl:ENSG00000173812 HPRD:15449; Vega:OTTHUMG00000133492
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    A121; ISO1; SUI1; EIF-1; EIF1A
    Orthologs
    Location:
    17q21.2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) 17 NC_000017.11 (41688875..41691646)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (39845127..39847898)

    Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene keratin 17 Neighboring gene keratin 42 pseudogene Neighboring gene RNA, 5S ribosomal pseudogene 442 Neighboring gene gastrin

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • RNA transport, organism-specific biosystem (from KEGG)
      RNA transport, organism-specific biosystemRNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) ...
    • RNA transport, conserved biosystem (from KEGG)
      RNA transport, conserved biosystemRNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) ...
    • Translation Factors, organism-specific biosystem (from WikiPathways)
      Translation Factors, organism-specific biosystemProtein synthesis is the ultimate step of gene expression and a key control point for regulation. In particular, it enables cells to rapidly manipulate protein production without new mRNA synthesis, ...
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    poly(A) RNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    translation factor activity, RNA binding TAS
    Traceable Author Statement
    more info
    PubMed 
    translation initiation factor activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    dosage compensation by inactivation of X chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of translational initiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    response to stress NAS
    Non-traceable Author Statement
    more info
    PubMed 
    translational initiation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    eukaryotic translation initiation factor 1
    Names
    protein translation factor SUI1 homolog
    sui1iso1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_005801.3NP_005792.1  eukaryotic translation initiation factor 1

      See identical proteins and their annotated locations for NP_005792.1

      Status: VALIDATED

      Source sequence(s)
      AA159721, BC005118, BU165055
      Consensus CDS
      CCDS11403.1
      UniProtKB/Swiss-Prot
      P41567
      UniProtKB/TrEMBL
      Q6IAV3
      Related
      ENSP00000419449, OTTHUMP00000164728, ENST00000469257, OTTHUMT00000257390
      Conserved Domains (1) summary
      cd11566
      Location:29112
      eIF1_SUI1; Eukaryotic initiation factor 1

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly

    Genomic

    1. NC_000017.11 Reference GRCh38.p7 Primary Assembly

      Range
      41688875..41691646
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CHM1_1.1

    Genomic

    1. NC_018928.2 Alternate CHM1_1.1

      Range
      40080633..40083404
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)