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    SLC2A10 solute carrier family 2 member 10 [ Homo sapiens (human) ]

    Gene ID: 81031, updated on 9-Jun-2016
    Official Symbol
    SLC2A10provided by HGNC
    Official Full Name
    solute carrier family 2 member 10provided by HGNC
    Primary source
    HGNC:HGNC:13444
    See related
    Ensembl:ENSG00000197496 HPRD:05851; MIM:606145; Vega:OTTHUMG00000032657
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ATS; GLUT10
    Summary
    This gene encodes a member of the class III facilitative glucose transporter family. The encoded protein plays a role in regulation of glucose homeostasis. Mutations in this gene have been associated with arterial tortuosity syndrome.[provided by RefSeq, Dec 2009]
    Orthologs
    Location:
    20q13.1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) 20 NC_000020.11 (46708358..46736347)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (45338279..45364986)

    Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene osteoclast stimulatory transmembrane protein Neighboring gene solute carrier family 13 member 3 Neighboring gene TP53 regulating kinase Neighboring gene RNA, 7SK small nuclear pseudogene 33 Neighboring gene ribosomal protein L13 pseudogene 14

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Clone Names

    • MGC126706

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    D-glucose transmembrane transporter activity TAS
    Traceable Author Statement
    more info
     
    glucose transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    sugar:proton symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    sugar:proton symporter activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    glucose import IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    glucose transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    glucose transport NAS
    Non-traceable Author Statement
    more info
    PubMed 
    proton transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
     
    endomembrane system IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane TAS
    Traceable Author Statement
    more info
     
    Preferred Names
    solute carrier family 2, facilitated glucose transporter member 10
    Names
    GLUT-10
    glucose transporter type 10
    solute carrier family 2 (facilitated glucose transporter), member 10

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_016284.1 RefSeqGene

      Range
      5001..31708
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_030777.3NP_110404.1  solute carrier family 2, facilitated glucose transporter member 10

      See identical proteins and their annotated locations for NP_110404.1

      Status: REVIEWED

      Source sequence(s)
      AF248053, AF321240
      Consensus CDS
      CCDS13402.1
      UniProtKB/Swiss-Prot
      O95528
      Related
      ENSP00000352216, OTTHUMP00000031212, ENST00000359271, OTTHUMT00000079578
      Conserved Domains (2) summary
      cd06174
      Location:14497
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00879
      Location:4508
      SP; MFS transporter, sugar porter (SP) family

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly

    Genomic

    1. NC_000020.11 Reference GRCh38.p7 Primary Assembly

      Range
      46708358..46736347
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011529064.2XP_011527366.1  

      Conserved Domains (2) summary
      cd06174
      Location:35351
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      COG0477
      Location:37344
      ProP; MFS family permease [Carbohydrate transport and metabolism, Amino acid transport and metabolism, Inorganic ion transport and metabolism, General function prediction only]
    2. XM_011529062.2XP_011527364.1  

      Conserved Domains (2) summary
      cd06174
      Location:35351
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      COG0477
      Location:37344
      ProP; MFS family permease [Carbohydrate transport and metabolism, Amino acid transport and metabolism, Inorganic ion transport and metabolism, General function prediction only]
    3. XM_011529063.2XP_011527365.1  

      Conserved Domains (2) summary
      cd06174
      Location:35351
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      pfam00083
      Location:38498
      Sugar_tr; Sugar (and other) transporter
    4. XM_011529065.2XP_011527367.1  

      Conserved Domains (1) summary
      cd06174
      Location:35351
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    5. XM_011529060.2XP_011527362.1  

      See identical proteins and their annotated locations for XP_011527362.1

      Conserved Domains (2) summary
      cd06174
      Location:35518
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00879
      Location:25529
      SP; MFS transporter, sugar porter (SP) family
    6. XM_017028087.1XP_016883576.1  

    7. XM_011529061.2XP_011527363.1  

      Conserved Domains (2) summary
      cd06174
      Location:17500
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00879
      Location:1511
      SP; MFS transporter, sugar porter (SP) family

    RNA

    1. XR_936641.2 RNA Sequence

    Alternate CHM1_1.1

    Genomic

    1. NC_018931.2 Alternate CHM1_1.1

      Range
      45241287..45267979
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)