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LRRTM2 leucine rich repeat transmembrane neuronal 2 [ Homo sapiens (human) ]

Gene ID: 26045, updated on 7-Dec-2014
Official Symbol
LRRTM2provided by HGNC
Official Full Name
leucine rich repeat transmembrane neuronal 2provided by HGNC
Primary source
HGNC:HGNC:19409
See related
Ensembl:ENSG00000146006; HPRD:17454; MIM:610868; Vega:OTTHUMG00000163535
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
See LRRTM2 in Epigenomics, MapViewer
Location:
5q31.2
Exon count:
2
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 5 NC_000005.10 (138869390..138875368, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (138205079..138211057, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA, C/D box 63 Neighboring gene heat shock 70kDa protein 9 (mortalin) Neighboring gene ribosomal protein L10a pseudogene 10 Neighboring gene catenin (cadherin-associated protein), alpha 1, 102kDa Neighboring gene SIL1 nucleotide exchange factor Neighboring gene ribosomal protein L12 pseudogene 21 Neighboring gene small nucleolar RNA, H/ACA box 74A Neighboring gene small nucleolar RNA host gene 4 (non-protein coding) Neighboring gene matrin 3

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Clone Names

  • FLJ52416, FLJ76283, FLJ99831

Gene Ontology Provided by GOA

Function Evidence Code Pubs
neurexin family protein binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
long-term synaptic potentiation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of receptor internalization IEA
Inferred from Electronic Annotation
more info
 
synapse organization IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cell junction IEA
Inferred from Electronic Annotation
more info
 
excitatory synapse IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
leucine-rich repeat transmembrane neuronal protein 2
Names
leucine-rich repeat transmembrane neuronal protein 2
leucine-rich repeat neuronal 2 protein
leucine-rich repeat transmembrane neuronal 2 protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015564.2NP_056379.1  leucine-rich repeat transmembrane neuronal protein 2 precursor

    See proteins identical to NP_056379.1

    Status: VALIDATED

    Source sequence(s)
    AB007876, AC011405, DA400927
    Consensus CDS
    CCDS47272.1
    UniProtKB/Swiss-Prot
    O43300
    Related
    ENSP00000274711, OTTHUMP00000224216, ENST00000274711, OTTHUMT00000374043
    Conserved Domains (2) summary
    cd00116
    Location:73324
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    pfam13855
    Location:133193
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000005.10 

    Range
    138869390..138875368
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018916.2 

    Range
    137637719..137643697
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

  1. AC_000137.1 

    Range
    133394868..133400836
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)