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MIR96 microRNA 96 [ Homo sapiens (human) ]

Gene ID: 407053, updated on 22-Jun-2014
Official Symbol
MIR96provided by HGNC
Official Full Name
microRNA 96provided by HGNC
Primary source
See related
Ensembl:ENSG00000199158; MIM:611606; miRBase:MI0000098
Gene type
RefSeq status
Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DFNA50; MIRN96; miR-96; miRNA96; hsa-mir-96
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. The microRNA encoded by this gene has been shown to down-regulate production of FOXO1, FOXO3, and microphthalmia-associated transcription factor-M, resulting in metastasis of certain tumors. Also, point mutations in the seed region of this microRNA are a cause of autosomal dominant, progressive hearing loss. [provided by RefSeq, Mar 2010]
See MIR96 in Epigenomics, MapViewer
Exon count :
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 7 NC_000007.14 (129774692..129774769, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (129414532..129414609, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene nuclear respiratory factor 1 Neighboring gene RNA, 5S ribosomal pseudogene 244 Neighboring gene microRNA 182 Neighboring gene microRNA 183 Neighboring gene ubiquitin-conjugating enzyme E2H

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • MicroRNAs in cancer, organism-specific biosystem (from KEGG)
    MicroRNAs in cancer, organism-specific biosystemMicroRNA (miRNA) is a cluster of small non-encoding RNA molecules of 21 - 23 nucleotides in length, which controls gene expression post-transcriptionally either via the degradation of target mRNAs or...
  • MicroRNAs in cancer, conserved biosystem (from KEGG)
    MicroRNAs in cancer, conserved biosystemMicroRNA (miRNA) is a cluster of small non-encoding RNA molecules of 21 - 23 nucleotides in length, which controls gene expression post-transcriptionally either via the degradation of target mRNAs or...

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.


  1. NR_029512.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly


  1. NC_000007.14 

    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef


  1. AC_000139.1 

    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1


  1. NC_018918.2 

    GenBank, FASTA, Sequence Viewer (Graphics)

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