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    PGAM4 phosphoglycerate mutase family member 4 [ Homo sapiens (human) ]

    Gene ID: 441531, updated on 8-Aug-2016
    Official Symbol
    PGAM4provided by HGNC
    Official Full Name
    phosphoglycerate mutase family member 4provided by HGNC
    Primary source
    HGNC:HGNC:21731
    See related
    Ensembl:ENSG00000226784 MIM:300567; Vega:OTTHUMG00000057865
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PGAM1; PGAM3; PGAM-B; dJ1000K24.1
    Summary
    This intronless gene appears to have arisen from a retrotransposition event, yet it is thought to be an expressed, protein-coding gene. The encoded protein is a member of the phosphoglycerate mutase family, a set of enzymes that catalyze the transfer of a phosphate group from 3-phosphoglycerate to 2-phosphoglycerate. [provided by RefSeq, May 2010]
    Orthologs
    Location:
    Xq13
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) X NC_000023.11 (77967961..77969638, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (77223458..77225135, complement)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene cytochrome c oxidase subunit 7B Neighboring gene ATPase copper transporting alpha Neighboring gene chromosome 4 open reading frame 46 pseudogene Neighboring gene phosphoglycerate kinase 1 Neighboring gene TATA-box binding protein associated factor 9b

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    bisphosphoglycerate 2-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    bisphosphoglycerate mutase activity IEA
    Inferred from Electronic Annotation
    more info
     
    phosphoglycerate mutase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    phosphoglycerate mutase activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    gluconeogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    glycolytic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    glycolytic process NAS
    Non-traceable Author Statement
    more info
    PubMed 
    positive regulation of sperm motility NAS
    Non-traceable Author Statement
    more info
    PubMed 
    regulation of pentose-phosphate shunt IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    extracellular exosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    sperm principal piece IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    phosphoglycerate mutase 4
    Names
    phosphoglycerate mutase family 3
    phosphoglycerate mutase processed protein
    probable phosphoglycerate mutase 4
    NP_001025062.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_021360.1 RefSeqGene

      Range
      5001..6678
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001029891.2NP_001025062.1  phosphoglycerate mutase 4

      See identical proteins and their annotated locations for NP_001025062.1

      Status: REVIEWED

      Source sequence(s)
      AF465731, BG875904, U76194
      Consensus CDS
      CCDS35338.1
      UniProtKB/Swiss-Prot
      Q8N0Y7
      Related
      ENSP00000412189, OTTHUMP00000063546, ENST00000458128, OTTHUMT00000128371
      Conserved Domains (1) summary
      PRK14115
      Location:4253
      gpmA; phosphoglyceromutase; Provisional

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p7 Primary Assembly

      Range
      77967961..77969638 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CHM1_1.1

    Genomic

    1. NC_018934.2 Alternate CHM1_1.1

      Range
      77116147..77117824 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)