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    plx pollux [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40704, updated on 16-Jul-2016
    Official Symbol
    plxprovided by FlyBase
    Official Full Name
    polluxprovided by FlyBase
    Primary source
    FLYBASE:FBgn0261261
    Locus tag
    Dmel_CG42612
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1093; CG14674; CG34122; CG42612; Dmel\CG42612
    Old locus tag
    Dmel_CG1093; Dmel_CG14674; Dmel_CG34122
    Location:
    83B9-83C1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    Release 6.07 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5685855..5712837)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1511577..1538559)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Autophagy-related 17 Neighboring gene CG2108 gene product from transcript CG2108-RA Neighboring gene CG2104 gene product from transcript CG2104-RB Neighboring gene castor Neighboring gene ncRNA

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    GTPase activator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Rab GTPase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    integrin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    cell adhesion mediated by integrin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of GTPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    CG42612 gene product from transcript CG42612-RE
    Names
    CG42612-PA
    CG42612-PC
    CG42612-PD
    CG42612-PE
    CG42612-PF
    plx-PA
    plx-PC
    plx-PD
    plx-PE
    plx-PF
    pollux

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      5685855..5712837
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275368.1NP_001262297.1  pollux, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262297.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KGK7
      Related
      FBpp0306963, FBtr0334947
      Conserved Domains (4) summary
      pfam11830
      Location:777826
      DUF3350; Domain of unknown function (DUF3350)
      smart00164
      Location:8791098
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cd01269
      Location:301547
      PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
      TIGR03495
      Location:11741252
      phage_LysB; phage lysis regulatory protein, LysB family
    2. NM_001170040.2NP_001163511.1  pollux, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163511.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JJ52
      Related
      FBpp0291301, FBtr0302091
      Conserved Domains (4) summary
      pfam11830
      Location:831880
      DUF3350; Domain of unknown function (DUF3350)
      smart00164
      Location:9331152
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cd01269
      Location:301601
      PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
      TIGR03495
      Location:12281306
      phage_LysB; phage lysis regulatory protein, LysB family
    3. NM_169095.3NP_730989.2  pollux, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730989.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IPP5
      Related
      FBpp0291302, FBtr0302092
      Conserved Domains (4) summary
      pfam11830
      Location:665714
      DUF3350; Domain of unknown function (DUF3350)
      smart00164
      Location:767986
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cd01269
      Location:135435
      PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
      TIGR03495
      Location:10621140
      phage_LysB; phage lysis regulatory protein, LysB family
    4. NM_001275369.1NP_001262298.1  pollux, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262298.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KG76
      Related
      FBpp0306964, FBtr0334948
      Conserved Domains (4) summary
      pfam11830
      Location:611660
      DUF3350; Domain of unknown function (DUF3350)
      smart00164
      Location:713932
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cd01269
      Location:135381
      PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
      TIGR03495
      Location:10081086
      phage_LysB; phage lysis regulatory protein, LysB family
    5. NM_169094.2NP_730988.1  pollux, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730988.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VNG9
      Related
      FBpp0291300, FBtr0302090
      Conserved Domains (4) summary
      smart00164
      Location:740959
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cd01269
      Location:108408
      PTB_TBC1D1_like; TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain
      pfam11830
      Location:642687
      DUF3350; Domain of unknown function (DUF3350)
      cl23720
      Location:9831074
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)