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    Itgb7 integrin beta 7 [ Mus musculus (house mouse) ]

    Gene ID: 16421, updated on 10-Sep-2016
    Official Symbol
    Itgb7provided by MGI
    Official Full Name
    integrin beta 7provided by MGI
    Primary source
    MGI:MGI:96616
    See related
    Ensembl:ENSMUSG00000001281 Vega:OTTMUSG00000030863
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ly69
    Orthologs
    Location:
    15 F3; 15 57.39 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 15 NC_000081.6 (102215994..102233405, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (102046426..102062366, complement)

    Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene sterol O-acyltransferase 2 Neighboring gene cysteine sulfinic acid decarboxylase Neighboring gene zinc finger protein 740 Neighboring gene retinoic acid receptor, gamma Neighboring gene predicted gene 9918

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    cell adhesion molecule binding ISO
    Inferred from Sequence Orthology
    more info
     
    receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    T cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    cell-matrix adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    cell-matrix adhesion involved in ameboidal cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    heterotypic cell-cell adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    integrin-mediated signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    leukocyte migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    leukocyte tethering or rolling ISO
    Inferred from Sequence Orthology
    more info
     
    receptor clustering ISO
    Inferred from Sequence Orthology
    more info
     
    substrate adhesion-dependent cell spreading ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integrin alpha4-beta7 complex ISO
    Inferred from Sequence Orthology
    more info
     
    integrin complex IEA
    Inferred from Electronic Annotation
    more info
     
    membrane ISO
    Inferred from Sequence Orthology
    more info
     
    receptor complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Preferred Names
    integrin beta-7
    Names
    M290 IEL antigen
    integrin beta-P

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013566.2NP_038594.2  integrin beta-7 precursor

      See identical proteins and their annotated locations for NP_038594.2

      Status: VALIDATED

      Source sequence(s)
      AI322899, AK078871, AK155594
      Consensus CDS
      CCDS49740.1
      UniProtKB/Swiss-Prot
      P26011
      Related
      ENSMUSP00000001327, OTTMUSP00000040198, ENSMUST00000001327, OTTMUST00000076379
      Conserved Domains (4) summary
      smart00187
      Location:50476
      INB; Integrin beta subunits (N-terminal portion of extracellular region)
      pfam07965
      Location:645716
      Integrin_B_tail; Integrin beta tail domain
      pfam07974
      Location:607635
      EGF_2; EGF-like domain
      pfam08725
      Location:749790
      Integrin_b_cyt; Integrin beta cytoplasmic domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000081.6 Reference GRCm38.p4 C57BL/6J

      Range
      102215994..102233405 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006520482.2XP_006520545.1  

      Conserved Domains (3) summary
      smart00187
      Location:50476
      INB; Integrin beta subunits (N-terminal portion of extracellular region)
      pfam07965
      Location:645716
      Integrin_B_tail; Integrin beta tail domain
      pfam07974
      Location:607635
      EGF_2; EGF-like domain
    2. XM_017316440.1XP_017171929.1  

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