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Cd68 CD68 antigen [ Mus musculus (house mouse) ]

Gene ID: 12514, updated on 26-Aug-2014
Official Symbol
Cd68provided by MGI
Official Full Name
CD68 antigenprovided by MGI
Primary source
MGI:88342
See related
Ensembl:ENSMUSG00000018774
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Lamp4; gp110; Scard1
See Cd68 in Epigenomics, MapViewer
Location:
11 B3; 11 42.86 cM
Exon count:
6
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 11 NC_000077.6 (69664213..69666646, complement)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene SRY (sex determining region Y)-box 15 Neighboring gene mannose-P-dolichol utilization defect 1 Neighboring gene microRNA 1934 Neighboring gene eukaryotic translation initiation factor 4A1 Neighboring gene SUMO/sentrin specific peptidase 3

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Lysosome, organism-specific biosystem (from KEGG)
    Lysosome, organism-specific biosystemLysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than...
  • Lysosome, conserved biosystem (from KEGG)
    Lysosome, conserved biosystemLysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than...
  • Macrophage markers, organism-specific biosystem (from WikiPathways)
    Macrophage markers, organism-specific biosystemOverview of macrophage markers. Based on [http://www.antibodybeyond.com/reviews/cell-markers/macrophage-marker.htm this list] and tissue-specific gene expression from [http://biogps.org/ GeneAtlas].

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
cellular response to organic substance IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
endosome IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
lysosome IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
macrosialin
Names
macrosialin

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001291058.1NP_001277987.1  macrosialin precursor

    See proteins identical to NP_001277987.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the functional protein.
    Source sequence(s)
    AW123877, BY210951, X68273
    Consensus CDS
    CCDS70216.1
    UniProtKB/Swiss-Prot
    P31996
    Conserved Domains (1) summary
    pfam01299
    Location:35326
    Blast Score: 486
    Lamp; Lysosome-associated membrane glycoprotein (Lamp)

RNA

  1. NR_110993.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an internal exon, compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
    Source sequence(s)
    AW123877, BY207885, BY210951, X68273

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000077.6 

    Range
    69664213..69666646
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006532109.1XP_006532172.1  

    Conserved Domains (1) summary
    pfam01299
    Location:35326
    Blast Score: 486
    Lamp; Lysosome-associated membrane glycoprotein (Lamp)

Alternate Mm_Celera

Genomic

  1. NW_001071864.1 

    Range
    6720..8411
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_009853.1: Suppressed sequence

    Description
    NM_009853.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.