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    Csf3 colony stimulating factor 3 (granulocyte) [ Mus musculus (house mouse) ]

    Gene ID: 12985, updated on 26-Jul-2015
    Official Symbol
    Csf3provided by MGI
    Official Full Name
    colony stimulating factor 3 (granulocyte)provided by MGI
    Primary source
    MGI:MGI:1339751
    See related
    Ensembl:ENSMUSG00000038067; Vega:OTTMUSG00000006406
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Csfg; G-CSF; MGI-IG
    Orthologs
    See Csf3 in Epigenomics, MapViewer
    Location:
    11 D; 11 62.45 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    105 current GRCm38.p3 (GCF_000001635.23) 11 NC_000077.6 (98701095..98704836)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (98562627..98564943)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene gasdermin A Neighboring gene uncharacterized LOC102634154 Neighboring gene proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 Neighboring gene predicted gene, 38985 Neighboring gene mediator complex subunit 24 Neighboring gene predicted gene, 31252 Neighboring gene thyroid hormone receptor alpha

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • Cytokine-cytokine receptor interaction, organism-specific biosystem (from KEGG)
      Cytokine-cytokine receptor interaction, organism-specific biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...
    • Cytokine-cytokine receptor interaction, conserved biosystem (from KEGG)
      Cytokine-cytokine receptor interaction, conserved biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...
    • Cytokines and Inflammatory Response (BioCarta), organism-specific biosystem (from WikiPathways)
      Cytokines and Inflammatory Response (BioCarta), organism-specific biosystemSee BioCarta version: http://www.biocarta.com/pathfiles/h_inflamPathway.asp
    • Hematopoietic cell lineage, organism-specific biosystem (from KEGG)
      Hematopoietic cell lineage, organism-specific biosystemBlood-cell development progresses from a hematopoietic stem cell (HSC), which can undergo either self-renewal or differentiation into a multilineage committed progenitor cell: a common lymphoid proge...
    • Hematopoietic cell lineage, conserved biosystem (from KEGG)
      Hematopoietic cell lineage, conserved biosystemBlood-cell development progresses from a hematopoietic stem cell (HSC), which can undergo either self-renewal or differentiation into a multilineage committed progenitor cell: a common lymphoid proge...
    • Jak-STAT signaling pathway, organism-specific biosystem (from KEGG)
      Jak-STAT signaling pathway, organism-specific biosystemThe Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for development and homeost...
    • Jak-STAT signaling pathway, conserved biosystem (from KEGG)
      Jak-STAT signaling pathway, conserved biosystemThe Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for development and homeost...
    • Malaria, organism-specific biosystem (from KEGG)
      Malaria, organism-specific biosystemPlasmodium protozoa are parasites that account for malaria infection. Sporozoite forms of the parasite are injected by mosquito bites under the skin and are carried to the liver where they develop in...
    • Malaria, conserved biosystem (from KEGG)
      Malaria, conserved biosystemPlasmodium protozoa are parasites that account for malaria infection. Sporozoite forms of the parasite are injected by mosquito bites under the skin and are carried to the liver where they develop in...
    • PI3K-Akt signaling pathway, organism-specific biosystem (from KEGG)
      PI3K-Akt signaling pathway, organism-specific biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...
    • PI3K-Akt signaling pathway, conserved biosystem (from KEGG)
      PI3K-Akt signaling pathway, conserved biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    cytokine activity ISO
    Inferred from Sequence Orthology
    more info
     
    cytokine activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    growth factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    granulocyte colony-stimulating factor

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009971.1NP_034101.1  granulocyte colony-stimulating factor precursor

      See identical proteins and their annotated locations for NP_034101.1

      Status: PROVISIONAL

      Source sequence(s)
      M13926
      Consensus CDS
      CCDS25360.1
      UniProtKB/Swiss-Prot
      P09920
      UniProtKB/TrEMBL
      Q0VB73
      Related
      ENSMUSP00000037762, OTTMUSP00000006785, ENSMUST00000038886, OTTMUST00000014593
      Conserved Domains (1) summary
      pfam00489
      Location:57205
      IL6; Interleukin-6/G-CSF/MGF family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p3 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p3 C57BL/6J

      Range
      98701095..98704836
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006532128.2XP_006532191.2  

      Conserved Domains (1) summary
      pfam00489
      Location:108256
      IL6; Interleukin-6/G-CSF/MGF family

    Alternate Mm_Celera

    Genomic

    1. AC_000033.1 Alternate Mm_Celera

      Range
      108355655..108357971
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)