Display Settings:

Format

Send to:

Choose Destination
    • Showing Current items.

    Efnb2 ephrin B2 [ Mus musculus (house mouse) ]

    Gene ID: 13642, updated on 13-Aug-2015
    Official Symbol
    Efnb2provided by MGI
    Official Full Name
    ephrin B2provided by MGI
    Primary source
    MGI:MGI:105097
    See related
    Ensembl:ENSMUSG00000001300; Vega:OTTMUSG00000022160
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Epl5; ELF-2; Eplg5; Htk-L; Lerk5; LERK-5; NLERK-1
    Orthologs
    See Efnb2 in Epigenomics, MapViewer
    Location:
    8 A1.1; 8 3.42 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    105 current GRCm38.p3 (GCF_000001635.23) 8 NC_000074.6 (8617235..8660773, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (8617439..8660773, complement)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 31135 Neighboring gene peroxiredoxin 3 pseudogene Neighboring gene predicted gene, 31463 Neighboring gene arginine and glutamate rich 1 Neighboring gene microRNA 7654 Neighboring gene IKAROS family zinc finger 5 pseudogene

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ephrin receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    ephrin receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    T cell costimulation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    angiogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    axon guidance IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    blood vessel morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    cell migration involved in sprouting angiogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    ephrin receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    ephrin receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    lymph vessel development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organismal development IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of keratinocyte proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    nephric duct morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    nervous system development IEA
    Inferred from Electronic Annotation
    more info
     
    organ morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cardiac muscle cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of chemotaxis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    focal adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    ephrin-B2
    Names
    EPH-related receptor tyrosine kinase ligand 5
    HTK ligand

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010111.5NP_034241.2  ephrin-B2 precursor

      See identical proteins and their annotated locations for NP_034241.2

      Status: PROVISIONAL

      Source sequence(s)
      AC138368, AC161867
      Consensus CDS
      CCDS22090.1
      UniProtKB/Swiss-Prot
      P52800
      UniProtKB/TrEMBL
      Q4FJM3
      Related
      ENSMUSP00000001319, OTTMUSP00000024973, ENSMUST00000001319, OTTMUST00000052622
      Conserved Domains (1) summary
      cd10426
      Location:32168
      Ephrin-B_Ectodomain; Ectodomain of Ephrin B

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p3 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p3 C57BL/6J

      Range
      8617235..8660773
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006508694.2XP_006508757.1  

      Conserved Domains (1) summary
      cl19115
      Location:32145
      Cupredoxin; Cupredoxin superfamily
    2. XM_011242036.1XP_011240338.1  

      Conserved Domains (1) summary
      cd10426
      Location:44168
      Ephrin-B_Ectodomain; Ectodomain of Ephrin B

    Alternate Mm_Celera

    Genomic

    1. AC_000030.1 Alternate Mm_Celera

      Range
      8790063..8833410
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)