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Atg5 autophagy related 5 [ Mus musculus (house mouse) ]

Gene ID: 11793, updated on 11-Aug-2014
Official Symbol
Atg5provided by MGI
Official Full Name
autophagy related 5provided by MGI
Primary source
MGI:1277186
See related
Ensembl:ENSMUSG00000038160
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Apg5l; Atg5l; Paddy; C88337; AW319544; 2010107M05Rik; 3110067M24Rik
See Atg5 in Epigenomics, MapViewer
Location:
10 B2; 10 23.24 cM
Exon count:
8
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 10 NC_000076.6 (44268358..44364299)

Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated glutamate (E)-rich protein 5, pseudogene 1 Neighboring gene coiled-coil domain containing 137 pseudogene Neighboring gene solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 pseudogene Neighboring gene microRNA 1929 Neighboring gene uncharacterized LOC102638474 Neighboring gene PR domain containing 1, with ZNF domain

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
contributes_to Atg8 ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
C-terminal protein lipidation IBA
Inferred from Biological aspect of Ancestor
more info
 
apoptotic process IEA
Inferred from Electronic Annotation
more info
 
autophagic vacuole assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
autophagy IMP
Inferred from Mutant Phenotype
more info
PubMed 
blood vessel remodeling IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to nitrogen starvation IBA
Inferred from Biological aspect of Ancestor
more info
 
heart contraction IMP
Inferred from Mutant Phenotype
more info
PubMed 
immune system process IEA
Inferred from Electronic Annotation
more info
 
innate immune response IEA
Inferred from Electronic Annotation
more info
 
mitochondrion degradation IBA
Inferred from Biological aspect of Ancestor
more info
 
negative regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of protein ubiquitination IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative stranded viral RNA replication IMP
Inferred from Mutant Phenotype
more info
 
nucleophagy IBA
Inferred from Biological aspect of Ancestor
more info
 
otolith development IMP
Inferred from Mutant Phenotype
more info
 
positive regulation of mucus secretion IMP
Inferred from Mutant Phenotype
more info
 
post-translational protein modification IDA
Inferred from Direct Assay
more info
PubMed 
regulation of cilium assembly IMP
Inferred from Mutant Phenotype
more info
 
regulation of cytokine secretion involved in immune response IMP
Inferred from Mutant Phenotype
more info
 
regulation of reactive oxygen species metabolic process IMP
Inferred from Mutant Phenotype
more info
 
regulation of release of sequestered calcium ion into cytosol IMP
Inferred from Mutant Phenotype
more info
 
response to drug IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to fungus IMP
Inferred from Mutant Phenotype
more info
 
vasodilation IMP
Inferred from Mutant Phenotype
more info
PubMed 
ventricular cardiac muscle cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
Atg12-Atg5-Atg16 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
ER-mitochondrion membrane contact site IDA
Inferred from Direct Assay
more info
 
autophagic vacuole IDA
Inferred from Direct Assay
more info
PubMed 
autophagic vacuole ISA
Inferred from Sequence Alignment
more info
PubMed 
axoneme IDA
Inferred from Direct Assay
more info
 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
membrane ISO
Inferred from Sequence Orthology
more info
 
pre-autophagosomal structure membrane IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
autophagy protein 5
Names
autophagy protein 5
autophagy-related 5

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053069.5NP_444299.1  autophagy protein 5

    See proteins identical to NP_444299.1

    Status: PROVISIONAL

    Source sequence(s)
    AC155642
    Consensus CDS
    CCDS23824.1
    UniProtKB/Swiss-Prot
    Q99J83
    Related
    ENSMUSP00000044769, ENSMUST00000039286
    Conserved Domains (1) summary
    pfam04106
    Location:79271
    Blast Score: 754
    APG5; Autophagy protein Apg5

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000076.6 

    Range
    44268358..44364299
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006512501.1XP_006512564.1  

    Conserved Domains (1) summary
    pfam04106
    Location:79179
    Blast Score: 352
    APG5; Autophagy protein Apg5
  2. XM_006512500.1XP_006512563.1  

    Conserved Domains (1) summary
    pfam04106
    Location:79160
    Blast Score: 353
    APG5; Autophagy protein Apg5

Alternate Mm_Celera

Genomic

  1. AC_000032.1 

    Range
    45141131..45237099
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)