Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    Pax7 paired box 7 [ Mus musculus (house mouse) ]

    Gene ID: 18509, updated on 24-Jun-2016
    Official Symbol
    Pax7provided by MGI
    Official Full Name
    paired box 7provided by MGI
    Primary source
    MGI:MGI:97491
    See related
    Ensembl:ENSMUSG00000028736 Vega:OTTMUSG00000010060
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pax-7
    Orthologs
    Location:
    4 E1; 4 70.83 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (139737059..139833026, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (139293996..139388883, complement)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene taste receptor, type 1, member 2 Neighboring gene predicted gene, 42334 Neighboring gene uncharacterized LOC108168982 Neighboring gene uncharacterized LOC102636380 Neighboring gene RIKEN cDNA 4933427I22 gene

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcription factor activity, RNA polymerase II core promoter sequence-specific IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcription factor activity, sequence-specific DNA binding TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    cartilage development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    chromatin remodeling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    dorsal/ventral neural tube patterning IDA
    Inferred from Direct Assay
    more info
    PubMed 
    embryonic skeletal system development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    muscle organ development IEA
    Inferred from Electronic Annotation
    more info
     
    muscle tissue morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    neuron fate commitment IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    organ morphogenesis TAS
    Traceable Author Statement
    more info
    PubMed 
    positive regulation of histone methylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of histone methylation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of myoblast proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of transcription from RNA polymerase II promoter IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of cell fate commitment IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of locomotion IC
    Inferred by Curator
    more info
    PubMed 
    regulation of protein binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated TAS
    Traceable Author Statement
    more info
    PubMed 
    skeletal muscle satellite cell commitment IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    skeletal muscle tissue development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    skeletal muscle tissue regeneration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    spinal cord association neuron differentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcription factor complex TAS
    Traceable Author Statement
    more info
    PubMed 
    Preferred Names
    paired box protein Pax-7
    Names
    paired box gene 7
    paired box transcription factor PAX7

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011039.2NP_035169.1  paired box protein Pax-7

      See identical proteins and their annotated locations for NP_035169.1

      Status: VALIDATED

      Source sequence(s)
      AL831790, AL844480
      Consensus CDS
      CCDS18850.1
      UniProtKB/Swiss-Prot
      P47239
      Related
      ENSMUSP00000030508, OTTMUSP00000010692, ENSMUST00000030508, OTTMUST00000023390
      Conserved Domains (3) summary
      pfam12360
      Location:345383
      Pax7; Paired box protein 7
      cd00086
      Location:216273
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      cd00131
      Location:34161
      PAX; Paired Box domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      139737059..139833026 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006538631.1XP_006538694.1  

      Conserved Domains (4) summary
      pfam12360
      Location:344382
      Pax7; Paired box protein 7
      cd00086
      Location:215272
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      cd00131
      Location:34160
      PAX; Paired Box domain
      pfam13551
      Location:56158
      HTH_29; Winged helix-turn helix
    2. XM_006538630.1XP_006538693.1  

      Conserved Domains (3) summary
      pfam12360
      Location:346384
      Pax7; Paired box protein 7
      cd00086
      Location:217274
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      cd00131
      Location:34162
      PAX; Paired Box domain
    3. XM_006538629.1XP_006538692.1  

      UniProtKB/TrEMBL
      G3UX36
      Related
      ENSMUSP00000133536, OTTMUSP00000054430, ENSMUST00000174681, OTTMUST00000097164
      Conserved Domains (3) summary
      pfam12360
      Location:347385
      Pax7; Paired box protein 7
      cd00086
      Location:218275
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      cd00131
      Location:34163
      PAX; Paired Box domain