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FKS1 1,3-beta-D-glucan synthase [ Saccharomyces cerevisiae S288c ]

Gene ID: 851055, updated on 7-Sep-2014
Gene symbol
FKS1
Gene description
1,3-beta-D-glucan synthase
Primary source
SGD:S000004334
Locus tag
YLR342W
Gene type
protein coding
RNA name
1,3-beta-D-glucan synthase
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
CND1; CWH53; ETG1; GSC1; PBR1
See FKS1 in MapViewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (809997..815627)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene ribosomal protein P0 Neighboring gene Spo77p Neighboring gene hypothetical protein Neighboring gene Gas2p

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by GO

Function Evidence Code Pubs
1,3-beta-D-glucan synthase activity IDA
Inferred from Direct Assay
more info
PubMed 
1,3-beta-D-glucan synthase activity IEA
Inferred from Electronic Annotation
more info
 
1,3-beta-D-glucan synthase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity, transferring glycosyl groups IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
(1->3)-beta-D-glucan biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
(1->3)-beta-D-glucan biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
(1->3)-beta-D-glucan biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of endocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cell shape IEA
Inferred from Electronic Annotation
more info
 
regulation of cell size IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
1,3-beta-D-glucan synthase complex IDA
Inferred from Direct Assay
more info
PubMed 
1,3-beta-D-glucan synthase complex IEA
Inferred from Electronic Annotation
more info
 
actin cortical patch IDA
Inferred from Direct Assay
more info
PubMed 
cellular bud neck IDA
Inferred from Direct Assay
more info
PubMed 
cellular bud tip IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane ISM
Inferred from Sequence Model
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
Names
1,3-beta-D-glucan synthase
NP_013446.1
  • Catalytic subunit of 1,3-beta-D-glucan synthase; functionally redundant with alternate catalytic subunit Gsc2p; binds to regulatory subunit Rho1p; involved in cell wall synthesis and maintenance; localizes to sites of cell wall remodeling; FKS1 has a paralog, GSC2, that arose from the whole genome duplication

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 

    Range
    809997..815627
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182231.1NP_013446.1  1,3-beta-D-glucan synthase [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_013446.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P38631
    Conserved Domains (3) summary
    pfam02364
    Location:8071632
    Glucan_synthase; 1,3-beta-glucan synthase component
    pfam12273
    Location:5102
    RCR; Chitin synthesis regulation, resistance to Congo red
    pfam14288
    Location:300411
    FKS1_dom1; 1,3-beta-glucan synthase subunit FKS1, domain-1