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NAB3 Nab3p [ Saccharomyces cerevisiae S288c ]

Gene ID: 855911, updated on 15-Jan-2015
Gene symbol
NAB3
Gene description
Nab3p
Primary source
SGD:S000006111
Locus tag
YPL190C
Gene type
protein coding
RNA name
Nab3p
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
HMD1
See NAB3 in MapViewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (185317..187725, complement)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Prm3p Neighboring gene hypothetical protein Neighboring gene Coa2p Neighboring gene Gup2p

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by GO

Function Evidence Code Pubs
RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
RNA binding IEA
Inferred from Electronic Annotation
more info
 
mRNA binding IDA
Inferred from Direct Assay
more info
PubMed 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
transcription regulatory region RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
CUT catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
antisense RNA transcript catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
mRNA 3'-end processing IMP
Inferred from Mutant Phenotype
more info
PubMed 
nuclear mRNA surveillance IMP
Inferred from Mutant Phenotype
more info
PubMed 
snRNA 3'-end processing IMP
Inferred from Mutant Phenotype
more info
PubMed 
snoRNA 3'-end processing IMP
Inferred from Mutant Phenotype
more info
PubMed 
tRNA 3'-end processing IMP
Inferred from Mutant Phenotype
more info
PubMed 
termination of RNA polymerase II transcription, exosome-dependent IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
Nrd1 complex IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
Nab3p
NP_015134.1
  • RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p); complex interacts with exosome to mediate 3'-end formation of some mRNAs, snRNAs, snoRNAs, and CUTs; required for termination of non-poly(A) transcripts and efficient splicing; Nrd1-Nab3 pathway appears to have a role in rapid suppression of some genes when cells are shifted to poor growth conditions, indicating role for Nrd1-Nab3 in regulating cellular response to nutrient availability

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 

    Range
    185317..187725
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184004.1NP_015134.1  Nab3p [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_015134.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P38996
    Conserved Domains (2) summary
    COG0724
    Location:295439
    COG0724; RNA-binding proteins (RRM domain) [General function prediction only]
    cd12342
    Location:331401
    RRM_Nab3p; RNA recognition motif in yeast nuclear polyadenylated RNA-binding protein 3 (Nab3p) and similar proteins