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PRNP prion protein [ Ovis aries (sheep) ]

Gene ID: 493887, updated on 17-May-2015
Gene symbol
PRNP
Gene description
prion protein
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Also known as
Prp; SIP; PRPC
Orthologs
See PRNP in MapViewer
Location:
chromosome: 13
Exon count:
3
Annotation release Status Assembly Chr Location
101 current Oar_v3.1 (GCF_000298735.1) 13 NC_019470.1 (46208471..46229267)
101 current Oori1 (GCF_000765115.1) Unplaced Scaffold NW_011942462.1 (1258609..1279182)

Chromosome 13 - NC_019470.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105609929 Neighboring gene DIP2 disco-interacting protein 2 homolog C (Drosophila) Neighboring gene zinc finger, MYND-type containing 11 Neighboring gene uncharacterized LOC105609932 Neighboring gene uncharacterized LOC105616712 Neighboring gene prion protein 2 (dublet) Neighboring gene prion protein (testis specific)

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Prion diseases, organism-specific biosystem (from KEGG)
    Prion diseases, organism-specific biosystemPrion diseases, also termed transmissible spongiform encephalopathies (TSEs), are a group of fatal neurodegenerative diseases that affect humans and a number of other animal species. The etiology of ...
  • Prion diseases, conserved biosystem (from KEGG)
    Prion diseases, conserved biosystemPrion diseases, also termed transmissible spongiform encephalopathies (TSEs), are a group of fatal neurodegenerative diseases that affect humans and a number of other animal species. The etiology of ...
Products Interactant Other Gene Complex Source Pubs Description
Preferred Names
major prion protein
Names
major prion protein
prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009481.1NP_001009481.1  major prion protein precursor

    See identical proteins and their annotated locations for NP_001009481.1

    Status: PROVISIONAL

    Source sequence(s)
    U67922
    UniProtKB/Swiss-Prot
    P23907
    UniProtKB/TrEMBL
    Q27H92
    Conserved Domains (2) summary
    smart00157
    Location:25243
    PRP; Major prion protein
    pfam11587
    Location:130
    Prion_bPrPp; Major prion protein bPrPp - N terminal

RefSeqs of Annotated Genomes: Ovis aries Annotation Release 101

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Oar_v3.1 Primary Assembly

Genomic

  1. NC_019470.1 Reference Oar_v3.1 Primary Assembly

    Range
    46208471..46229267
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012188090.1XP_012043480.1  

    See identical proteins and their annotated locations for XP_012043480.1

Alternate Oori1

Genomic

  1. NW_011942462.1 Alternate Oori1

    Range
    1258609..1279182
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)