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RAP1 DNA-binding transcription factor RAP1 [ Saccharomyces cerevisiae S288c ]

Gene ID: 855505, updated on 19-Mar-2015
Gene symbol
RAP1
Gene description
DNA-binding transcription factor RAP1
Primary source
SGD:S000005160
Locus tag
YNL216W
Gene type
protein coding
RNA name
DNA-binding transcription factor RAP1
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
GRF1; TBA1; TUF1
See RAP1 in MapViewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (241689..244172)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene ssDNA-dependent ATPase MGS1 Neighboring gene putative serine/threonine-protein phosphatase Neighboring gene Ies2p Neighboring gene Pex17p

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Process Evidence Code Pubs
chromatin silencing at silent mating-type cassette IGI
Inferred from Genetic Interaction
more info
PubMed 
chromatin silencing at telomere IGI
Inferred from Genetic Interaction
more info
PubMed 
establishment of chromatin silencing at telomere IPI
Inferred from Physical Interaction
more info
PubMed 
establishment of protein localization to chromatin IPI
Inferred from Physical Interaction
more info
PubMed 
establishment of protein localization to telomere IPI
Inferred from Physical Interaction
more info
PubMed 
negative regulation of chromatin silencing IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
protection from non-homologous end joining at telomere IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
telomere maintenance IMP
Inferred from Mutant Phenotype
more info
PubMed 
telomere maintenance via telomere lengthening IDA
Inferred from Direct Assay
more info
PubMed 
telomere maintenance via telomere lengthening IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
chromosome IEA
Inferred from Electronic Annotation
more info
 
chromosome, telomeric region IEA
Inferred from Electronic Annotation
more info
 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
nuclear chromosome IDA
Inferred from Direct Assay
more info
PubMed 
nuclear chromosome, telomeric region IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
telosome IDA
Inferred from Direct Assay
more info
PubMed 
Names
DNA-binding transcription factor RAP1
NP_014183.1
  • Essential DNA-binding transcription regulator that binds many loci; involved in transcription activation and repression, chromatin silencing, and telomere length maintenance; relocalizes to the cytosol in response to hypoxia; conserved protein with an N-terminal BRCT domain, a central region with homology to the Myb DNA binding domain, and a C-terminal Rap1-specific protein-interaction domain (RCT domain)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    241689..244172
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183054.1NP_014183.1  DNA-binding transcription factor RAP1 [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_014183.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P11938
    Conserved Domains (3) summary
    cd11653
    Location:727824
    rap1_RCT; C-terminal domain of RAP1 recruits proteins to telomeres
    cd11655
    Location:446550
    rap1_myb-like; DNA-binding modules of yeast Rap1 and related proteins
    cd00027
    Location:128196
    BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...