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Cd36 CD36 molecule (thrombospondin receptor) [ Rattus norvegicus (Norway rat) ]

Gene ID: 29184, updated on 22-Jun-2014
Official Symbol
Cd36provided by RGD
Official Full Name
CD36 molecule (thrombospondin receptor)provided by RGD
Primary source
RGD:2301
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Also known as
Fat
Summary
fatty acid translocase; involved in long-chain fatty acid (LCFA) transport; important in fatty acid metabolism and insulin function [RGD, Feb 2006]
Annotation information
Annotation category: partial on reference assembly
See Cd36 in MapViewer
Location:
4q11
Exon count :
14
Annotation release Status Assembly Chr Location
104 current Rnor_5.0 (GCF_000001895.4) 4 NC_005103.3 (14125297..14166434)

Chromosome 4 - NC_005103.3Genomic Context describing neighboring genes Neighboring gene platelet glycoprotein 4-like Neighboring gene MLV-related proviral Env polyprotein-like Neighboring gene similar to fatty acid translocase/CD36 Neighboring gene sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
high-density lipoprotein particle binding ISO
Inferred from Sequence Orthology
more info
 
lipid binding ISO
Inferred from Sequence Orthology
more info
 
lipoprotein particle binding ISO
Inferred from Sequence Orthology
more info
 
lipoteichoic acid receptor activity ISO
Inferred from Sequence Orthology
more info
 
low-density lipoprotein particle binding ISO
Inferred from Sequence Orthology
more info
 
low-density lipoprotein receptor activity ISO
Inferred from Sequence Orthology
more info
 
oleic acid binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
thrombospondin receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
transforming growth factor beta binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
apoptotic cell clearance ISO
Inferred from Sequence Orthology
more info
 
cGMP-mediated signaling ISO
Inferred from Sequence Orthology
more info
 
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
cell surface receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
cellular response to bacterial lipopeptide ISO
Inferred from Sequence Orthology
more info
 
cellular response to hydroperoxide ISO
Inferred from Sequence Orthology
more info
 
cellular response to insulin stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to lipopolysaccharide ISO
Inferred from Sequence Orthology
more info
 
cellular response to lipoteichoic acid ISO
Inferred from Sequence Orthology
more info
 
cholesterol transport ISO
Inferred from Sequence Orthology
more info
 
defense response to Gram-positive bacterium ISO
Inferred from Sequence Orthology
more info
 
digestive tract development IEP
Inferred from Expression Pattern
more info
PubMed 
fatty acid metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
fatty acid metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
fatty acid oxidation IMP
Inferred from Mutant Phenotype
more info
PubMed 
fatty acid transport IDA
Inferred from Direct Assay
more info
PubMed 
fatty acid transport IEP
Inferred from Expression Pattern
more info
PubMed 
fatty acid transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
lipid storage ISO
Inferred from Sequence Orthology
more info
 
lipoprotein transport ISO
Inferred from Sequence Orthology
more info
 
long-chain fatty acid import ISO
Inferred from Sequence Orthology
more info
 
long-chain fatty acid metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
long-chain fatty acid transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
low-density lipoprotein particle clearance ISO
Inferred from Sequence Orthology
more info
 
low-density lipoprotein particle mediated signaling ISO
Inferred from Sequence Orthology
more info
 
negative regulation of angiogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
negative regulation of growth of symbiont in host ISO
Inferred from Sequence Orthology
more info
 
negative regulation of systemic arterial blood pressure IMP
Inferred from Mutant Phenotype
more info
 
negative regulation of transcription factor import into nucleus ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
nitric oxide mediated signal transduction ISO
Inferred from Sequence Orthology
more info
 
pattern recognition receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
phagocytosis, recognition ISO
Inferred from Sequence Orthology
more info
 
plasma lipoprotein particle clearance ISO
Inferred from Sequence Orthology
more info
 
plasma membrane long-chain fatty acid transport ISO
Inferred from Sequence Orthology
more info
 
positive regulation of I-kappaB kinase/NF-kappaB signaling ISO
Inferred from Sequence Orthology
more info
 
positive regulation of MAPK cascade ISO
Inferred from Sequence Orthology
more info
 
positive regulation of blood coagulation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of blood microparticle formation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell-matrix adhesion ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cholesterol storage ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cytokine secretion IMP
Inferred from Mutant Phenotype
more info
 
positive regulation of interleukin-12 production ISO
Inferred from Sequence Orthology
more info
 
positive regulation of interleukin-6 production ISO
Inferred from Sequence Orthology
more info
 
positive regulation of macrophage cytokine production ISO
Inferred from Sequence Orthology
more info
 
positive regulation of macrophage derived foam cell differentiation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of peptidyl-tyrosine phosphorylation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of phagocytosis, engulfment ISO
Inferred from Sequence Orthology
more info
 
positive regulation of reactive oxygen species metabolic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of tumor necrosis factor production ISO
Inferred from Sequence Orthology
more info
 
receptor-mediated endocytosis ISO
Inferred from Sequence Orthology
more info
 
regulation of removal of superoxide radicals ISO
Inferred from Sequence Orthology
more info
 
response to activity IEP
Inferred from Expression Pattern
more info
PubMed 
response to drug IEP
Inferred from Expression Pattern
more info
PubMed 
response to estradiol IEP
Inferred from Expression Pattern
more info
PubMed 
response to growth hormone IEP
Inferred from Expression Pattern
more info
PubMed 
response to mechanical stimulus IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to nutrient IEP
Inferred from Expression Pattern
more info
PubMed 
signal transduction IDA
Inferred from Direct Assay
more info
PubMed 
triglyceride metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
apical part of cell IDA
Inferred from Direct Assay
more info
PubMed 
caveola IDA
Inferred from Direct Assay
more info
PubMed 
cell surface IDA
Inferred from Direct Assay
more info
PubMed 
cell surface ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 
external side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular IDA
Inferred from Direct Assay
more info
PubMed 
intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
PubMed 
membrane raft ISO
Inferred from Sequence Orthology
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
protein complex IDA
Inferred from Direct Assay
more info
 
sarcolemma IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
platelet glycoprotein 4
Names
platelet glycoprotein 4
GPIV
PAS-4
GPIIIB
PAS IV
glycoprotein IIIb
fatty acid translocase
platelet glycoprotein IV
adipocyte membrane protein
fatty acid transport protein
collagen type I receptor thrombospondin receptor
CD36 antigen (collagen type I receptor, thrombospondin receptor)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031561.2NP_113749.2  platelet glycoprotein 4

    See proteins identical to NP_113749.2

    Status: PROVISIONAL

    Source sequence(s)
    BC072543
    UniProtKB/TrEMBL
    Q6IMX5
    Conserved Domains (1) summary
    pfam01130
    Location:12464
    Blast Score: 1366
    CD36; CD36 family

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_5.0 Primary Assembly

Genomic

  1. NC_005103.3 

    Range
    14125297..14166434
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000072.1 

    Range
    12880238..12941086
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

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