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Atxn1 ataxin 1 [ Mus musculus (house mouse) ]

Gene ID: 20238, updated on 17-Dec-2014
Official Symbol
Atxn1provided by MGI
Official Full Name
ataxin 1provided by MGI
Primary source
MGI:MGI:104783
See related
Ensembl:ENSMUSG00000046876
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Atx1; Sca1; C85907; Gm10786; 2900016G23Rik; ENSMUSG00000074917
See Atxn1 in Epigenomics, MapViewer
Location:
13 A5; 13 21.98 cM
Exon count:
9
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 13 NC_000079.6 (45549755..45964991, complement)

Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene myosin regulatory light chain interacting protein Neighboring gene predicted gene, 34582 Neighboring gene guanosine monophosphate reductase Neighboring gene RIKEN cDNA 5033430I15 gene Neighboring gene predicted gene, 34901

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • mRNA processing, organism-specific biosystem (from WikiPathways)
    mRNA processing, organism-specific biosystemAdapted from Reactome, see: [http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_1675.1 REACT 1675.1] This process describes the conversion of precursor messenger RNA into mature messenge...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
poly(G) binding ISO
Inferred from Sequence Orthology
more info
 
poly(U) RNA binding ISO
Inferred from Sequence Orthology
more info
 
protein C-terminus binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein self-association ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with nuclear RNA export factor complex ISO
Inferred from Sequence Orthology
more info
 
nuclear inclusion body IDA
Inferred from Direct Assay
more info
PubMed 
nuclear inclusion body ISO
Inferred from Sequence Orthology
more info
 
nuclear matrix ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
ataxin-1
Names
ataxin-1
spinocerebellar ataxia 1 homolog

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199304.1NP_001186233.1  ataxin-1 isoform b

    See proteins identical to NP_001186233.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 2 and 3 both encode the same isoform (b).
    Source sequence(s)
    AC154817, AK048268, AK165114, BE993799
    Consensus CDS
    CCDS26483.1
    UniProtKB/Swiss-Prot
    P54254
    Related
    ENSMUSP00000129890, ENSMUST00000167708
    Conserved Domains (2) summary
    pfam08517
    Location:550664
    AXH; Ataxin-1 and HBP1 module (AXH)
    pfam12547
    Location:391421
    ATXN-1_C; Capicua transcriptional repressor modulator
  2. NM_001199305.1NP_001186234.1  ataxin-1 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a).
    Source sequence(s)
    AC154817, AK048268, AK165114, BE993799
    Consensus CDS
    CCDS56877.1
    UniProtKB/TrEMBL
    J3QPR1
    UniProtKB/Swiss-Prot
    P54254
    Related
    ENSMUSP00000137439, ENSMUST00000180110
    Conserved Domains (2) summary
    pfam08517
    Location:550672
    AXH; Ataxin-1 and HBP1 module (AXH)
    pfam12547
    Location:391421
    ATXN-1_C; Capicua transcriptional repressor modulator
  3. NM_009124.6NP_033150.2  ataxin-1 isoform b

    See proteins identical to NP_033150.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 2 and 3 both encode the same isoform (b).
    Source sequence(s)
    AC154817, AK048268, AK165114, BE993799
    Consensus CDS
    CCDS26483.1
    UniProtKB/Swiss-Prot
    P54254
    Related
    ENSMUSP00000089217, ENSMUST00000091628
    Conserved Domains (2) summary
    pfam08517
    Location:550664
    AXH; Ataxin-1 and HBP1 module (AXH)
    pfam12547
    Location:391421
    ATXN-1_C; Capicua transcriptional repressor modulator

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000079.6 

    Range
    45549755..45964991
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006516881.1XP_006516944.1  

    See proteins identical to XP_006516944.1

    UniProtKB/Swiss-Prot
    P54254
    Conserved Domains (2) summary
    pfam08517
    Location:550664
    AXH; Ataxin-1 and HBP1 module (AXH)
    pfam12547
    Location:391421
    ATXN-1_C; Capicua transcriptional repressor modulator

Alternate Mm_Celera

Genomic

  1. AC_000035.1 

    Range
    46625620..47041595
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)