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SPCH transcription factor SPEECHLESS [ Arabidopsis thaliana (thale cress) ]

Gene ID: 835402, updated on 8-Jan-2015
Gene symbol
SPCH
Gene description
transcription factor SPEECHLESS
Primary source
TAIR:AT5G53210
Locus tag
AT5G53210
Gene type
protein coding
RNA name
transcription factor SPEECHLESS
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
MFH8.15; SPCH; SPEECHLESS
See SPCH in MapViewer
Location:
chromosome: 5
Exon count:
3
Sequence:
Chromosome: 5; NC_003076.8 (21586606..21588941, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene transcription factor TRY Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description
  • Encodes a basic helix-loop-helix (bHLH) transcription factor that is necessary and sufficient for the asymmetric divisions that establish the stomatal lineage in Arabidopsis thaliana. Expression of SPCH in young epidermal cells allows these cells to make asymmetric divisions. SPCH is a substrate of a kinase MPK3 and MPK6.
NM_124700.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 
sequence-specific DNA binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Process Evidence Code Pubs
regulation of cell proliferation RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
regulation of transcription, DNA-templated TAS
Traceable Author Statement
more info
PubMed 
stomatal complex development IMP
Inferred from Mutant Phenotype
more info
PubMed 
stomatal complex morphogenesis RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISM
Inferred from Sequence Model
more info
 
Names
transcription factor SPEECHLESS
NP_200133.2
  • basic helix-loop-helix (bHLH) DNA-binding superfamily protein SPEECHLESS (SPCH); CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR:AT3G06120.1); Has 3630 Blast hits to 3207 proteins in 306 species: Archae - 0; Bacteria - 54; Metazoa - 562; Fungi - 218; Plants - 2401; Viruses - 108; Other Eukaryotes - 287 (source: NCBI BLink).

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 

    Range
    21586606..21588941
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_124700.2NP_200133.2  transcription factor SPEECHLESS [Arabidopsis thaliana]

    See proteins identical to NP_200133.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q700C7
    Conserved Domains (1) summary
    cd00083
    Location:97155
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...