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    Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 [ Mus musculus (house mouse) ]

    Gene ID: 13162, updated on 26-Jul-2015
    Official Symbol
    Slc6a3provided by MGI
    Official Full Name
    solute carrier family 6 (neurotransmitter transporter, dopamine), member 3provided by MGI
    Primary source
    MGI:MGI:94862
    See related
    Ensembl:ENSMUSG00000021609
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    DAT; Dat1
    Orthologs
    See Slc6a3 in Epigenomics, MapViewer
    Location:
    13 C1; 13 40.1 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    105 current GRCm38.p3 (GCF_000001635.23) 13 NC_000079.6 (73535528..73578672)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (73674195..73716120)

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA D630045M09 gene Neighboring gene lysophosphatidylcholine acyltransferase 1 Neighboring gene CLPTM1-like Neighboring gene telomerase reverse transcriptase

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    dopamine binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    dopamine transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    dopamine transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    dopamine:sodium symporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    drug binding ISO
    Inferred from Sequence Orthology
    more info
     
    monoamine transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    neurotransmitter:sodium symporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    protease binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein N-terminus binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein phosphatase 2A binding ISO
    Inferred from Sequence Orthology
    more info
     
    receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    symporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    adenohypophysis development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ammonium transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ammonium transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    cation transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    dopamine biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    dopamine catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    dopamine transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    dopamine transport ISO
    Inferred from Sequence Orthology
    more info
     
    lactation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    locomotory behavior IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    locomotory behavior IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    monoamine transport ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    neurotransmitter transport ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of multicellular organism growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    prepulse inhibition IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of dopamine metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to cAMP ISO
    Inferred from Sequence Orthology
    more info
     
    response to cocaine IDA
    Inferred from Direct Assay
    more info
    PubMed 
    response to ethanol ISO
    Inferred from Sequence Orthology
    more info
     
    sensory perception of smell IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    sodium ion transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    axon ISO
    Inferred from Sequence Orthology
    more info
     
    cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    flotillin complex ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    neuron projection ISO
    Inferred from Sequence Orthology
    more info
     
    neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    sodium-dependent dopamine transporter
    Names
    DA transporter
    dopamine transporter 1
    solute carrier family 6 member 3

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010020.3NP_034150.1  sodium-dependent dopamine transporter

      See identical proteins and their annotated locations for NP_034150.1

      Status: PROVISIONAL

      Source sequence(s)
      AC154547, AC158359
      Consensus CDS
      CCDS26632.1
      UniProtKB/Swiss-Prot
      Q61327
      Related
      ENSMUSP00000022100, ENSMUST00000022100
      Conserved Domains (1) summary
      cl00456
      Location:60613
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p3 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p3 C57BL/6J

      Range
      73535528..73578672
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006517084.2XP_006517147.1  

      Conserved Domains (1) summary
      cl00456
      Location:60385
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    2. XM_006517083.2XP_006517146.1  

      Conserved Domains (1) summary
      cl00456
      Location:60569
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    3. XM_006517082.2XP_006517145.1  

      See identical proteins and their annotated locations for XP_006517145.1

      UniProtKB/Swiss-Prot
      Q61327
      Conserved Domains (1) summary
      cl00456
      Location:60613
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    RNA

    1. XR_382422.2 RNA Sequence

    Alternate Mm_Celera

    Genomic

    1. AC_000035.1 Alternate Mm_Celera

      Range
      75865546..75907463
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)