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    let-60 Ras protein let-60 [ Caenorhabditis elegans ]

    Gene ID: 178104, updated on 19-Jul-2016
    Gene symbol
    let-60
    Gene description
    Ras protein let-60
    Primary source
    WormBase:WBGene00002335
    Locus tag
    CELE_ZK792.6
    Gene type
    protein coding
    RNA name
    Ras protein let-60
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    See let-60 in Map Viewer
    Location:
    chromosome: IV
    Exon count:
    4
    Sequence:
    Chromosome: IV; NC_003282.8 (11689046..11691077, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene ncRNA Neighboring gene hypothetical protein Neighboring gene ncRNA Neighboring gene hypothetical protein

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    GTP binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    GTPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Rap guanyl-nucleotide exchange factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT Ras guanyl-nucleotide exchange factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    phospholipase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    associative learning IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    axon extension IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    body morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    embryo development ending in birth or egg hatching IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    epidermal growth factor receptor signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    hermaphrodite genitalia development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    locomotion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    muscle organ development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    muscle organ development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of vulval development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    nematode larval development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    nematode larval development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    nematode larval development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    oogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    oviposition IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    NOT positive regulation of GTPase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of receptor localization to synapse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of vulval development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    positive regulation of vulval development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of vulval development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    receptor-mediated endocytosis IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    regulation of cell fate specification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of cell projection organization IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of cell projection organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    reproduction IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    reproduction IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    response to starvation IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    secretion by cell IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    short-term memory IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    small GTPase mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cell cortex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Names
    Ras protein let-60
    NP_502213.3
    • Confirmed by transcript evidence

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      11689046..11691077 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069812.3NP_502213.3  Ras protein let-60 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502213.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P22981
      Conserved Domains (2) summary
      cd04138
      Location:3164
      H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B
      PTZ00369
      Location:1184
      PTZ00369; Ras-like protein; Provisional