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Kiss1r KISS1 receptor [ Mus musculus (house mouse) ]

Gene ID: 114229, updated on 19-Jul-2014
Official Symbol
Kiss1rprovided by MGI
Official Full Name
KISS1 receptorprovided by MGI
Primary source
MGI:2148793
See related
Ensembl:ENSMUSG00000035773
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gpr54; KiSS-1
See Kiss1r in Epigenomics, MapViewer
Location:
10 C1; 10
Exon count:
6
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 10 NC_000076.6 (79916971..79922565)

Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene mediator complex subunit 16 Neighboring gene R3H domain containing 4 Neighboring gene AT rich interactive domain 3A (BRIGHT-like) Neighboring gene WD repeat domain 18

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
G-protein coupled peptide receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
G-protein coupled peptide receptor activity ISO
Inferred from Sequence Orthology
more info
 
G-protein coupled receptor activity ISO
Inferred from Sequence Orthology
more info
PubMed 
neuropeptide binding ISO
Inferred from Sequence Orthology
more info
 
neuropeptide receptor activity ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
signal transducer activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
G-protein coupled receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
activation of MAPKK activity ISO
Inferred from Sequence Orthology
more info
 
arachidonic acid secretion ISO
Inferred from Sequence Orthology
more info
 
calcium-mediated signaling ISO
Inferred from Sequence Orthology
more info
 
negative regulation of cell migration IPI
Inferred from Physical Interaction
more info
PubMed 
negative regulation of cell proliferation IPI
Inferred from Physical Interaction
more info
PubMed 
negative regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
neuropeptide signaling pathway ISO
Inferred from Sequence Orthology
more info
 
positive regulation of hormone secretion ISO
Inferred from Sequence Orthology
more info
 
positive regulation of stress fiber assembly ISO
Inferred from Sequence Orthology
more info
 
positive regulation of synaptic transmission ISO
Inferred from Sequence Orthology
more info
 
signal transduction IDA
Inferred from Direct Assay
more info
PubMed 
synaptic transmission ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cell surface IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane ISO
Inferred from Sequence Orthology
more info
 
integral component of plasma membrane ISO
Inferred from Sequence Orthology
more info
PubMed 
intracellular ISO
Inferred from Sequence Orthology
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
kiSS-1 receptor
Names
kiSS-1 receptor
kiSS-1R
mOT7T175
metastin receptor
kisspeptins receptor
G protein-coupled receptor 54
G-protein coupled receptor 54
G-protein coupled receptor OT7T175
orphan G protein-coupled receptor 54

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053244.5NP_444474.1  kiSS-1 receptor

    See proteins identical to NP_444474.1

    Status: VALIDATED

    Source sequence(s)
    AC151846, AK039628, AK139303
    Consensus CDS
    CCDS23998.1
    UniProtKB/TrEMBL
    B2CP06
    UniProtKB/Swiss-Prot
    Q91V45
    Related
    ENSMUSP00000040516, ENSMUST00000045529
    Conserved Domains (2) summary
    pfam00001
    Location:65323
    Blast Score: 436
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam10328
    Location:51168
    Blast Score: 87
    7TM_GPCR_Srx; Serpentine type 7TM GPCR chemoreceptor Srx

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000076.6 

    Range
    79916971..79922565
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513077.1XP_006513140.1  

    See proteins identical to XP_006513140.1

    UniProtKB/TrEMBL
    B2CP06
    UniProtKB/Swiss-Prot
    Q91V45
    Conserved Domains (2) summary
    pfam00001
    Location:65323
    Blast Score: 436
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam10328
    Location:51168
    Blast Score: 87
    7TM_GPCR_Srx; Serpentine type 7TM GPCR chemoreceptor Srx
  2. XM_006513079.1XP_006513142.1  

    See proteins identical to XP_006513142.1

    UniProtKB/TrEMBL
    C5H7S2
    Conserved Domains (2) summary
    pfam00001
    Location:65168
    Blast Score: 285
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam10320
    Location:53157
    Blast Score: 93
    7TM_GPCR_Srsx; Serpentine type 7TM GPCR chemoreceptor Srsx
  3. XM_006513076.1XP_006513139.1  

    See proteins identical to XP_006513139.1

    UniProtKB/TrEMBL
    B2CP06
    UniProtKB/Swiss-Prot
    Q91V45
    Conserved Domains (2) summary
    pfam00001
    Location:65323
    Blast Score: 436
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam10328
    Location:51168
    Blast Score: 87
    7TM_GPCR_Srx; Serpentine type 7TM GPCR chemoreceptor Srx
  4. XM_006513078.1XP_006513141.1  

    See proteins identical to XP_006513141.1

    UniProtKB/TrEMBL
    C5H7S2
    Conserved Domains (2) summary
    pfam00001
    Location:65168
    Blast Score: 285
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam10320
    Location:53157
    Blast Score: 93
    7TM_GPCR_Srsx; Serpentine type 7TM GPCR chemoreceptor Srsx
  5. XM_006513080.1XP_006513143.1  

    Conserved Domains (1) summary
    pfam00001
    Location:65167
    Blast Score: 260
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RNA

  1. XR_380346.1 RNA Sequence

Alternate Mm_Celera

Genomic

  1. AC_000032.1 

    Range
    80931781..80937083
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)