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    Trpv1 transient receptor potential cation channel, subfamily V, member 1 [ Mus musculus (house mouse) ]

    Gene ID: 193034, updated on 26-Jul-2015
    Official Symbol
    Trpv1provided by MGI
    Official Full Name
    transient receptor potential cation channel, subfamily V, member 1provided by MGI
    Primary source
    MGI:MGI:1341787
    See related
    Ensembl:ENSMUSG00000005952; Vega:OTTMUSG00000006125
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Vr1; VR-1; OTRPC1; TRPV1beta; TRPV1alpha
    Orthologs
    See Trpv1 in Epigenomics, MapViewer
    Location:
    11 45.25 cM; 11 B3
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    105 current GRCm38.p3 (GCF_000001635.23) 11 NC_000077.6 (73231024..73261322)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (73051761..73074009)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene cystinosis, nephropathic Neighboring gene sedoheptulokinase Neighboring gene transient receptor potential cation channel, subfamily V, member 3 Neighboring gene predicted gene, 40196 Neighboring gene aspartoacylase

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding ISO
    Inferred from Sequence Orthology
    more info
     
    calcium channel activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    calcium-release channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    calmodulin binding ISO
    Inferred from Sequence Orthology
    more info
     
    cation channel activity ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    cation channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    cation transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    chloride channel regulator activity ISO
    Inferred from Sequence Orthology
    more info
     
    excitatory extracellular ligand-gated ion channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    ion channel activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ligand-gated ion channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    phosphoprotein binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    temperature-gated ion channel activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transmembrane signaling receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    behavioral response to pain IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    calcium ion transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    calcium ion transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    calcium ion transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    calcium ion transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    calcium ion transport ISO
    Inferred from Sequence Orthology
    more info
     
    catagen IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cation transmembrane transport ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    cation transport ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    cellular response to ATP ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to alkaloid ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to cytokine stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    detection of chemical stimulus involved in sensory perception of pain IDA
    Inferred from Direct Assay
    more info
    PubMed 
    detection of chemical stimulus involved in sensory perception of pain IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    detection of temperature stimulus involved in sensory perception of pain IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    detection of temperature stimulus involved in sensory perception of pain IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    diet induced thermogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    fever generation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    glutamate secretion ISO
    Inferred from Sequence Orthology
    more info
     
    ion transmembrane transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ion transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    lipid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    microglial cell activation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of establishment of blood-brain barrier ISO
    Inferred from Sequence Orthology
    more info
     
    peptide secretion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cytosolic calcium ion concentration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of gastric acid secretion ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of nitric oxide biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    response to heat IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to heat ISO
    Inferred from Sequence Orthology
    more info
     
    response to organonitrogen compound IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to pH IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to pH ISO
    Inferred from Sequence Orthology
    more info
     
    response to pain IDA
    Inferred from Direct Assay
    more info
    PubMed 
    response to pain IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    sensory perception of mechanical stimulus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    sensory perception of pain IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    smooth muscle contraction involved in micturition IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    temperature homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    thermoception ISO
    Inferred from Sequence Orthology
    more info
     
    transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    transport IEA
    Inferred from Electronic Annotation
    more info
     
    urinary bladder smooth muscle contraction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    external side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane ISO
    Inferred from Sequence Orthology
    more info
     
    intrinsic component of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    membrane ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    membrane ISO
    Inferred from Sequence Orthology
    more info
     
    neuron projection IDA
    Inferred from Direct Assay
    more info
    PubMed 
    neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    postsynaptic membrane ISO
    Inferred from Sequence Orthology
    more info
     
    synapse ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    transient receptor potential cation channel subfamily V member 1
    Names
    capsaicin receptor
    cation channel
    deltaN-TRPv1
    osm-9-like TRP channel 1
    transient receptor potential cation channel V1
    vanilloid receptor 1
    vanilloid receptor subtype 1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001001445.2NP_001001445.1  transient receptor potential cation channel subfamily V member 1

      See identical proteins and their annotated locations for NP_001001445.1

      Status: VALIDATED

      Source sequence(s)
      AK051315, AL663116
      Consensus CDS
      CCDS25003.1
      UniProtKB/TrEMBL
      Q3V318
      UniProtKB/Swiss-Prot
      Q704Y3
      Related
      ENSMUSP00000099585, OTTMUSP00000006426, ENSMUST00000102526, OTTMUST00000013851
      Conserved Domains (2) summary
      cd00204
      Location:200354
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      TIGR00870
      Location:52825
      trp; transient-receptor-potential calcium channel protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p3 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p3 C57BL/6J

      Range
      73231024..73261322
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006532580.2XP_006532643.2  

      Conserved Domains (2) summary
      cd00204
      Location:216370
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      TIGR00870
      Location:68841
      trp; transient-receptor-potential calcium channel protein

    Reference GRCm38.p3 NOD/MrkTac

    Genomic

    1. NT_166317.2 Reference GRCm38.p3 NOD/MrkTac

      Range
      322988..353246
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006536293.2XP_006536356.2  

      Conserved Domains (2) summary
      cd00204
      Location:216370
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      TIGR00870
      Location:68841
      trp; transient-receptor-potential calcium channel protein

    Alternate Mm_Celera

    Genomic

    1. AC_000033.1 Alternate Mm_Celera

      Range
      80771410..80798588
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)