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    Akap5 A kinase (PRKA) anchor protein 5 [ Mus musculus (house mouse) ]

    Gene ID: 238276, updated on 5-Jul-2015
    Official Symbol
    Akap5provided by MGI
    Official Full Name
    A kinase (PRKA) anchor protein 5provided by MGI
    Primary source
    MGI:MGI:2685104
    See related
    Ensembl:ENSMUSG00000021057; Vega:OTTMUSG00000016317
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    P150; Gm258; AKAP-5; AKAP150; AKAP 150; BB098886; 3526401B18Rik
    Orthologs
    See Akap5 in Epigenomics, MapViewer
    Location:
    12; 12 C3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    105 current GRCm38.p3 (GCF_000001635.23) 12 NC_000078.6 (76324402..76334151)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (77425878..77435138)

    Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Neighboring gene predicted gene, 34868 Neighboring gene predicted gene, 40443 Neighboring gene zinc finger and BTB domain containing 25 Neighboring gene zinc finger and BTB domain containing 1 Neighboring gene RIKEN cDNA 4930426I24 gene

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • G Protein Signaling Pathways, organism-specific biosystem (from WikiPathways)
      G Protein Signaling Pathways, organism-specific biosystemG proteins, short for guanine nucleotide-binding proteins, are a family of proteins involved in second messenger cascades. G proteins are so called because they function as "molecular switches". They...
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    G-protein coupled receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    GABA receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    actin binding ISO
    Inferred from Sequence Orthology
    more info
     
    adenylate cyclase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    adenylate cyclase binding ISO
    Inferred from Sequence Orthology
    more info
     
    cadherin binding ISO
    Inferred from Sequence Orthology
    more info
     
    calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
     
    kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein kinase A regulatory subunit binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein phosphatase 2B binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    amylase secretion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular protein complex disassembly ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of adenylate cyclase activity ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of ion transport ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of potassium ion transport ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of NFAT protein import into nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of adenylate cyclase activity ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cAMP biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of calcium ion transport into cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of dendrite morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein kinase A signaling ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    protein targeting IEA
    Inferred from Electronic Annotation
    more info
     
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    asymmetric synapse ISO
    Inferred from Sequence Orthology
    more info
     
    basolateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    cell IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    dendrite membrane ISO
    Inferred from Sequence Orthology
    more info
     
    dendritic shaft ISO
    Inferred from Sequence Orthology
    more info
     
    dendritic spine ISO
    Inferred from Sequence Orthology
    more info
     
    dendritic spine membrane ISO
    Inferred from Sequence Orthology
    more info
     
    filopodium membrane ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
     
    protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    A-kinase anchor protein 5
    Names
    A-kinase anchor protein 150 kDa
    cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001101471.1NP_001094941.1  A-kinase anchor protein 5

      See identical proteins and their annotated locations for NP_001094941.1

      Status: VALIDATED

      Source sequence(s)
      AC120002
      Consensus CDS
      CCDS49092.1
      UniProtKB/Swiss-Prot
      D3YVF0
      Related
      ENSMUSP00000114495, ENSMUST00000154078
      Conserved Domains (1) summary
      pfam03832
      Location:71101
      WSK; WSK motif

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p3 C57BL/6J

    Genomic

    1. NC_000078.6 Reference GRCm38.p3 C57BL/6J

      Range
      76324402..76334151
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006515842.2XP_006515905.1  

      UniProtKB/TrEMBL
      H3BIV5
      Conserved Domains (1) summary
      pfam03832
      Location:78108
      WSK; WSK motif

    Alternate Mm_Celera

    Genomic

    1. AC_000034.1 Alternate Mm_Celera

      Range
      77415834..77425026
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)