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Mybpc3 myosin binding protein C, cardiac [ Mus musculus (house mouse) ]

Gene ID: 17868, updated on 5-Apr-2015
Official Symbol
Mybpc3provided by MGI
Official Full Name
myosin binding protein C, cardiacprovided by MGI
Primary source
MGI:MGI:102844
See related
Ensembl:ENSMUSG00000002100; Vega:OTTMUSG00000014369
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Orthologs
See Mybpc3 in MapViewer
Location:
2; 2 E1
Exon count:
35
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 2 NC_000068.7 (91118114..91136518)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (90958301..90976673)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 39874 Neighboring gene spleen focus forming virus (SFFV) proviral integration oncogene Neighboring gene MAP-kinase activating death domain Neighboring gene nuclear receptor subfamily 1, group H, member 3 Neighboring gene acid phosphatase 2, lysosomal

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
actin binding IEA
Inferred from Electronic Annotation
more info
 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
myosin binding ISO
Inferred from Sequence Orthology
more info
 
myosin heavy chain binding IPI
Inferred from Physical Interaction
more info
PubMed 
myosin heavy chain binding ISO
Inferred from Sequence Orthology
more info
 
structural constituent of cytoskeleton TAS
Traceable Author Statement
more info
PubMed 
structural constituent of muscle ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
cardiac muscle contraction IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
heart morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
heart morphogenesis ISO
Inferred from Sequence Orthology
more info
 
muscle contraction IDA
Inferred from Direct Assay
more info
PubMed 
myosin filament assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of heart contraction IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of heart rate IMP
Inferred from Mutant Phenotype
more info
PubMed 
sarcomere organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
ventricular cardiac muscle tissue morphogenesis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
A band IDA
Inferred from Direct Assay
more info
PubMed 
A band ISO
Inferred from Sequence Orthology
more info
 
cytoskeleton TAS
Traceable Author Statement
more info
PubMed 
myofibril IDA
Inferred from Direct Assay
more info
PubMed 
myosin filament IEA
Inferred from Electronic Annotation
more info
 
sarcomere IDA
Inferred from Direct Assay
more info
PubMed 
sarcomere ISO
Inferred from Sequence Orthology
more info
 
striated muscle myosin thick filament ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
myosin-binding protein C, cardiac-type
Names
myosin-binding protein C, cardiac-type
C-protein, cardiac muscle isoform
cardiac C-protein
cardiac MyBP-C

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008653.2NP_032679.2  myosin-binding protein C, cardiac-type

    See identical proteins and their annotated locations for NP_032679.2

    Status: VALIDATED

    Source sequence(s)
    AK146886
    Consensus CDS
    CCDS50631.1
    UniProtKB/TrEMBL
    Q3UIK0
    Related
    ENSMUSP00000127070, OTTMUSP00000015227, ENSMUST00000169776, OTTMUST00000033992
    Conserved Domains (7) summary
    cd00096
    Location:12021269
    Ig; Immunoglobulin domain
    cd05748
    Location:9941066
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd05894
    Location:660772
    Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
    smart00410
    Location:9851066
    IG_like; Immunoglobulin like
    cd00063
    Location:776866
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:11851274
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:567633
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p3 C57BL/6J

    Range
    91118114..91136518
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011239341.1XP_011237643.1  

    See identical proteins and their annotated locations for XP_011237643.1

    Conserved Domains (7) summary
    cd00096
    Location:12021269
    Ig; Immunoglobulin domain
    cd05748
    Location:9941066
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd05894
    Location:660772
    Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
    smart00410
    Location:9851066
    IG_like; Immunoglobulin like
    cd00063
    Location:776866
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:11851274
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:567633
    Ig; Immunoglobulin domain
  2. XM_006498882.2XP_006498945.1  

    Related
    ENSMUSP00000119994, OTTMUSP00000042060, ENSMUST00000137942, OTTMUST00000034060
    Conserved Domains (7) summary
    cd00096
    Location:12011268
    Ig; Immunoglobulin domain
    cd05748
    Location:9931065
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd05894
    Location:659771
    Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
    smart00410
    Location:9841065
    IG_like; Immunoglobulin like
    cd00063
    Location:775865
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:11841273
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:566632
    Ig; Immunoglobulin domain

Alternate Mm_Celera

Genomic

  1. AC_000024.1 Alternate Mm_Celera

    Range
    92502890..92521291
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)