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    Map2 microtubule-associated protein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25595, updated on 7-Feb-2016
    Official Symbol
    Map2provided by RGD
    Official Full Name
    microtubule-associated protein 2provided by RGD
    Primary source
    RGD:3044
    See related
    Ensembl:ENSRNOG00000011841; Vega:OTTRNOG00000002174
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
    Also known as
    MAP2R; Mtap2
    Summary
    regulates and organizes microtubules; may serve as a scaffolding protein for neuromodulatory activities [RGD, Feb 2006]
    Orthologs
    See Map2 in MapViewer
    Location:
    9q32
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    105 current Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (73334908..73462972)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 9 NC_005108.3 (73837509..74095431, complement)

    Chromosome 9 - NC_005108.4Genomic Context describing neighboring genes Neighboring gene crystallin, gamma F Neighboring gene splicing factor, arginine/serine-rich 12-like Neighboring gene unc-80 homolog, NALCN activator Neighboring gene uncharacterized LOC103693232 Neighboring gene ribulose-5-phosphate-3-epimerase

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
     
    dystroglycan binding IEA
    Inferred from Electronic Annotation
    more info
     
    dystroglycan binding ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    microtubule binding IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    axonogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    axonogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to organic substance IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to organic substance ISO
    Inferred from Sequence Orthology
    more info
     
    central nervous system neuron development IEA
    Inferred from Electronic Annotation
    more info
     
    central nervous system neuron development ISO
    Inferred from Sequence Orthology
    more info
     
    dendrite development ISO
    Inferred from Sequence Orthology
    more info
     
    dendrite morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    dendrite morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    establishment of cell polarity ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule bundle formation IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule bundle formation ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    neuron projection development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    neuron projection development ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of axonogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    response to estradiol IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to progesterone IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    CA3 pyramidal cell dendrite IEA
    Inferred from Electronic Annotation
    more info
     
    CA3 pyramidal cell dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    cell body ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    dendrite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    dendritic shaft IEA
    Inferred from Electronic Annotation
    more info
     
    dendritic shaft ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule associated complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    neuron projection IDA
    Inferred from Direct Assay
    more info
    PubMed 
    neuron projection ISO
    Inferred from Sequence Orthology
    more info
     
    neuronal cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    neuronal cell body IEA
    Inferred from Electronic Annotation
    more info
     
    neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    neuronal postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
     
    neuronal postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear periphery IEA
    Inferred from Electronic Annotation
    more info
     
    nuclear periphery ISO
    Inferred from Sequence Orthology
    more info
     
    nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
     
    protein complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    rough endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    smooth endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    microtubule-associated protein 2
    Names
    MAP-2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013066.1NP_037198.1  microtubule-associated protein 2

      See identical proteins and their annotated locations for NP_037198.1

      Status: PROVISIONAL

      Source sequence(s)
      X54100
      UniProtKB/TrEMBL
      Q64715
      Related
      ENSRNOP00000042029, OTTRNOP00000002098, ENSRNOT00000043627, OTTRNOT00000003653
      Conserved Domains (2) summary
      pfam00418
      Location:16901720
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:3741507
      MAP2_projctn; MAP2/Tau projection domain

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005108.4 Reference Rnor_6.0 Primary Assembly

      Range
      73334908..73462972
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008767207.1XP_008765429.1  

      See identical proteins and their annotated locations for XP_008765429.1

      UniProtKB/TrEMBL
      Q78DZ1
      Conserved Domains (1) summary
      pfam00418
      Location:332362
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    2. XM_008767208.1XP_008765430.1  

      See identical proteins and their annotated locations for XP_008765430.1

      UniProtKB/Swiss-Prot
      P15146
      Conserved Domains (1) summary
      pfam00418
      Location:332362
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
    3. XM_008767198.1XP_008765420.1  

      See identical proteins and their annotated locations for XP_008765420.1

      UniProtKB/TrEMBL
      F1LNK0
      Conserved Domains (2) summary
      pfam00418
      Location:17761806
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:4601593
      MAP2_projctn; MAP2/Tau projection domain
    4. XM_008767206.1XP_008765428.1  

      Related
      ENSRNOP00000075849, OTTRNOP00000002099, ENSRNOT00000092445, OTTRNOT00000003654
      Conserved Domains (2) summary
      pfam00418
      Location:16941724
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:3781511
      MAP2_projctn; MAP2/Tau projection domain
    5. XM_008767197.1XP_008765419.1  

      See identical proteins and their annotated locations for XP_008765419.1

      UniProtKB/TrEMBL
      F1LNK0
      Related
      ENSRNOP00000050877, ENSRNOT00000045766
      Conserved Domains (2) summary
      pfam00418
      Location:17761806
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:4601593
      MAP2_projctn; MAP2/Tau projection domain
    6. XM_008767203.1XP_008765425.1  

      Conserved Domains (2) summary
      pfam00418
      Location:17761806
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:4601593
      MAP2_projctn; MAP2/Tau projection domain
    7. XM_008767200.1XP_008765422.1  

      Conserved Domains (2) summary
      pfam00418
      Location:17751805
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:4601592
      MAP2_projctn; MAP2/Tau projection domain
    8. XM_008767202.1XP_008765424.1  

      Conserved Domains (2) summary
      pfam00418
      Location:17721802
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:4561589
      MAP2_projctn; MAP2/Tau projection domain
    9. XM_008767199.1XP_008765421.1  

      Conserved Domains (2) summary
      pfam00418
      Location:17751805
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:4591592
      MAP2_projctn; MAP2/Tau projection domain
    10. XM_008767204.1XP_008765426.1  

      Conserved Domains (2) summary
      pfam00418
      Location:16941724
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:3781511
      MAP2_projctn; MAP2/Tau projection domain
    11. XM_008767205.1XP_008765427.1  

      Conserved Domains (2) summary
      pfam00418
      Location:16901720
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:3741507
      MAP2_projctn; MAP2/Tau projection domain
    12. XM_008767201.1XP_008765423.1  

      Conserved Domains (2) summary
      pfam00418
      Location:17751805
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:4591592
      MAP2_projctn; MAP2/Tau projection domain
    13. XM_006245100.2XP_006245162.1  

      Conserved Domains (2) summary
      pfam00418
      Location:16171647
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:3011434
      MAP2_projctn; MAP2/Tau projection domain

    Alternate Rn_Celera

    Genomic

    1. AC_000077.1 Alternate Rn_Celera

      Range
      65377941..65459391
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)