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    Cryba1 crystallin, beta A1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25583, updated on 19-Jan-2016
    Official Symbol
    Cryba1provided by RGD
    Official Full Name
    crystallin, beta A1provided by RGD
    Primary source
    RGD:2415
    See related
    Ensembl:ENSRNOG00000008700
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
    Also known as
    BA3A1C; beta-A3
    Summary
    a lens structural component [RGD, Feb 2006]
    Orthologs
    See Cryba1 in MapViewer
    Location:
    10q24-q25
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    105 current Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (65161152..65167504)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 10 NC_005109.3 (66458061..66480390, complement)

    Chromosome 10 - NC_005109.4Genomic Context describing neighboring genes Neighboring gene myosin XVIIIa Neighboring gene bolA-like 1-like Neighboring gene bolA-like protein 2-like Neighboring gene nuclear fragile X mental retardation protein interacting protein 2 Neighboring gene 60S ribosomal protein L27a pseudogene

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    structural constituent of eye lens IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    camera-type eye development ISO
    Inferred from Sequence Orthology
    more info
     
    lens development in camera-type eye IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    negative regulation of ERK1 and ERK2 cascade IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of TOR signaling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of cytokine production IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of phosphatidylinositol 3-kinase signaling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of protein kinase B signaling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of anoikis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    visual perception ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    beta-crystallin A3
    Names
    beta-A3 crystallin

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013056.1NP_037188.1  beta-crystallin A3

      See identical proteins and their annotated locations for NP_037188.1

      Status: VALIDATED

      Source sequence(s)
      AABR07030057
      UniProtKB/Swiss-Prot
      P14881
      Related
      ENSRNOP00000011608, ENSRNOT00000011608
      Conserved Domains (2) summary
      smart00247
      Location:125213
      XTALbg; Beta/gamma crystallins
      pfam00030
      Location:32116
      Crystall; Beta/Gamma crystallin

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005109.4 Reference Rnor_6.0 Primary Assembly

      Range
      65161152..65167504
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000078.1 Alternate Rn_Celera

      Range
      61589011..61595363 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)