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csf1ra colony stimulating factor 1 receptor, a [ Danio rerio (zebrafish) ]

Gene ID: 64274, updated on 16-Aug-2014
Official Symbol
csf1raprovided by ZNC
Official Full Name
colony stimulating factor 1 receptor, aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-001205-1
See related
Ensembl:ENSDARG00000007889
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
fms; csf1r; CSF-1R; M-CSF-R; panther
Annotation information
Annotation category: partial on reference assembly
See csf1ra in MapViewer
Location:
chromosome: 15
Exon count:
21
Annotation release Status Assembly Chr Location
103 current Zv9 (GCF_000002035.4) 15 NC_007126.5 (43673437..43704831)

Chromosome 15 - NC_007126.5Genomic Context describing neighboring genes Neighboring gene glutamate receptor, ionotropic, AMPA 4a Neighboring gene glutamate receptor, ionotropic, AMPA 4a Neighboring gene platelet-derived growth factor D-like Neighboring gene cytoplasmic dynein 2 heavy chain 1-like

Genomic Sequence:
NC_007126.5 chromosome 15 reference Zv9 Primary Assembly
  • Cytokine-cytokine receptor interaction, organism-specific biosystem (from KEGG)
    Cytokine-cytokine receptor interaction, organism-specific biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...
  • Cytokine-cytokine receptor interaction, conserved biosystem (from KEGG)
    Cytokine-cytokine receptor interaction, conserved biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...
  • Endocytosis, organism-specific biosystem (from KEGG)
    Endocytosis, organism-specific biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
  • Endocytosis, conserved biosystem (from KEGG)
    Endocytosis, conserved biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
  • neural crest development, organism-specific biosystem (from WikiPathways)
    neural crest development, organism-specific biosystemThis pathway displays genes required for different processes in neural crest development. It is based on genetic and signaling interactions.

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity, transferring phosphorus-containing groups IEA
Inferred from Electronic Annotation
more info
 
transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
developmental pigmentation IGI
Inferred from Genetic Interaction
more info
PubMed 
developmental pigmentation IMP
Inferred from Mutant Phenotype
more info
PubMed 
immune system process IEA
Inferred from Electronic Annotation
more info
 
inflammatory response IEA
Inferred from Electronic Annotation
more info
 
innate immune response IEA
Inferred from Electronic Annotation
more info
 
macrophage chemotaxis IMP
Inferred from Mutant Phenotype
more info
PubMed 
microglia differentiation IMP
Inferred from Mutant Phenotype
more info
 
osteoclast development IMP
Inferred from Mutant Phenotype
more info
 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of macrophage chemotaxis IMP
Inferred from Mutant Phenotype
more info
 
positive regulation of neural retina development IMP
Inferred from Mutant Phenotype
more info
 
protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
transmembrane receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 
xanthophore differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
macrophage colony-stimulating factor 1 receptor
Names
macrophage colony-stimulating factor 1 receptor
pfe
sal
salz
c-fms
CSF-1-R
pfeffer
CSF-1 receptor
fms proto-oncogene homolog
proto-oncogene fms homolog
proto-oncogene c-Fms homolog
NP_571747.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_131672.1NP_571747.1  macrophage colony-stimulating factor 1 receptor precursor

    See proteins identical to NP_571747.1

    Status: PROVISIONAL

    Source sequence(s)
    AF240639
    UniProtKB/TrEMBL
    B3DHL0
    UniProtKB/Swiss-Prot
    Q9I8N6
    Related
    ENSDARP00000089365, ENSDART00000098594
    Conserved Domains (7) summary
    cd05106
    Location:545918
    Blast Score: 2035
    PTKc_CSF-1R; Catalytic domain of the Protein Tyrosine Kinase, Colony-Stimulating Factor-1 Receptor
    cd00096
    Location:427509
    Blast Score: 81
    Ig; Immunoglobulin domain
    smart00410
    Location:222306
    Blast Score: 131
    IG_like; Immunoglobulin like
    pfam07714
    Location:584913
    Blast Score: 987
    Pkinase_Tyr; Protein tyrosine kinase
    pfam13895
    Location:117205
    Blast Score: 143
    Ig_2; Immunoglobulin domain
    pfam13927
    Location:212293
    Blast Score: 138
    Ig_3; Immunoglobulin domain
    cl11960
    Location:311410
    Blast Score: 149
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 103

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Zv9 Primary Assembly

Genomic

  1. NC_007126.5 

    Range
    43673437..43704831
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)