Display Settings:

Format

Send to:

Choose Destination

Nrl neural retina leucine zipper gene [ Mus musculus (house mouse) ]

Gene ID: 18185, updated on 17-Mar-2015
Official Symbol
Nrlprovided by MGI
Official Full Name
neural retina leucine zipper geneprovided by MGI
Primary source
MGI:MGI:102567
See related
Ensembl:ENSMUSG00000040632
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D14H14S46E
Summary
This gene encodes a member of the basic leucine zipper domain family of transcription factors. The encoded protein is preferentially expressed in the retina and is necessary for rod photoreceptor development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Orthologs
See Nrl in MapViewer
Location:
14 C3; 14 28.19 cM
Exon count:
5
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 14 NC_000080.6 (55518978..55524981, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (56137815..56143802, complement)

Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 16B Neighboring gene copine VI Neighboring gene phosphoenolpyruvate carboxykinase 2 (mitochondrial) Neighboring gene DDB1 and CUL4 associated factor 11

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
neural retina-specific leucine zipper protein
Names
neural retina-specific leucine zipper protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001136074.2NP_001129546.1  neural retina-specific leucine zipper protein

    See proteins identical to NP_001129546.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 3. Variants 1, 2, 3, and 4 encode the same protein.
    Source sequence(s)
    AC159002, AK044244, AK044316
    Consensus CDS
    CCDS27113.1
    UniProtKB/Swiss-Prot
    P54846
    UniProtKB/TrEMBL
    Q543Y0
    UniProtKB/TrEMBL
    Q8C8Y1
    Conserved Domains (2) summary
    pfam08383
    Location:67102
    Maf_N; Maf N-terminal region
    pfam03131
    Location:132222
    bZIP_Maf; bZIP Maf transcription factor
  2. NM_001271916.1NP_001258845.1  neural retina-specific leucine zipper protein

    See proteins identical to NP_001258845.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) represents the longest transcript. Variants 1, 2, 3, and 4 encode the same protein.
    Source sequence(s)
    AC159002, AK044244, AK044275
    Consensus CDS
    CCDS27113.1
    UniProtKB/Swiss-Prot
    P54846
    UniProtKB/TrEMBL
    Q543Y0
    UniProtKB/TrEMBL
    Q8C8Y1
    Conserved Domains (2) summary
    pfam08383
    Location:67102
    Maf_N; Maf N-terminal region
    pfam03131
    Location:132222
    bZIP_Maf; bZIP Maf transcription factor
  3. NM_001271917.1NP_001258846.1  neural retina-specific leucine zipper protein

    See proteins identical to NP_001258846.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 3. Variants 1, 2, 3, and 4 encode the same protein.
    Source sequence(s)
    AC159002, AK044244, AK044316
    Consensus CDS
    CCDS27113.1
    UniProtKB/Swiss-Prot
    P54846
    UniProtKB/TrEMBL
    Q543Y0
    UniProtKB/TrEMBL
    Q8C8Y1
    Conserved Domains (2) summary
    pfam08383
    Location:67102
    Maf_N; Maf N-terminal region
    pfam03131
    Location:132222
    bZIP_Maf; bZIP Maf transcription factor
  4. NM_008736.3NP_032762.1  neural retina-specific leucine zipper protein

    See proteins identical to NP_032762.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 3. Variants 1, 2, 3, and 4 encode the same protein.
    Source sequence(s)
    AC159002, AK044275
    Consensus CDS
    CCDS27113.1
    UniProtKB/Swiss-Prot
    P54846
    UniProtKB/TrEMBL
    Q543Y0
    Related
    ENSMUSP00000107035, ENSMUST00000111404
    Conserved Domains (2) summary
    pfam08383
    Location:67102
    Maf_N; Maf N-terminal region
    pfam03131
    Location:132222
    bZIP_Maf; bZIP Maf transcription factor

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000080.6 Reference GRCm38.p3 C57BL/6J

    Range
    55518978..55524981
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006518688.1XP_006518751.1  

    Conserved Domains (1) summary
    pfam03131
    Location:34124
    bZIP_Maf; bZIP Maf transcription factor

Alternate Mm_Celera

Genomic

  1. AC_000036.1 Alternate Mm_Celera

    Range
    53323817..53329829
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)