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Adora2b adenosine A2b receptor [ Mus musculus (house mouse) ]

Gene ID: 11541, updated on 8-Dec-2014
Official Symbol
Adora2bprovided by MGI
Official Full Name
adenosine A2b receptorprovided by MGI
Primary source
MGI:MGI:99403
Locus tag
RP23-330N10.1
See related
Ensembl:ENSMUSG00000018500; Vega:OTTMUSG00000005854
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A2b; A2BR; A2BAR; AA2BR; AI480866; AI605384
See Adora2b in Epigenomics, MapViewer
Location:
11 B2; 11
Exon count:
2
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 11 NC_000077.6 (62248984..62266452)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene sperm antigen with calponin homology and coiled-coil domains 1 Neighboring gene endothelial differentiation-related factor 1 pseudogene Neighboring gene surfeit gene 1 pseudogene Neighboring gene zinc finger SWIM-type containing 7 Neighboring gene tetratricopeptide repeat domain 19 Neighboring gene nuclear receptor co-repressor 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Clone Names

  • MGC144574, MGC144575

Gene Ontology Provided by MGI

Function Evidence Code Pubs
G-protein coupled adenosine receptor activity ISO
Inferred from Sequence Orthology
more info
 
G-protein coupled receptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
signal transducer activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
adenosine receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
adenylate cyclase-activating G-protein coupled receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to extracellular stimulus IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of collagen biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cAMP biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cAMP biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cGMP biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of catecholamine secretion ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of chemokine production IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of chronic inflammatory response to non-antigenic stimulus IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of guanylate cyclase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of interleukin-6 production IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of mast cell degranulation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of norepinephrine secretion ISO
Inferred from Sequence Orthology
more info
 
positive regulation of steroid biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of vasodilation ISO
Inferred from Sequence Orthology
more info
 
positive regulation vascular endothelial growth factor production IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of angiogenesis ISO
Inferred from Sequence Orthology
more info
 
relaxation of vascular smooth muscle IMP
Inferred from Mutant Phenotype
more info
PubMed 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cell surface ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
adenosine receptor A2b
Names
adenosine receptor A2b
A2b, Rs

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007413.4NP_031439.2  adenosine receptor A2b

    See proteins identical to NP_031439.2

    Status: PROVISIONAL

    Source sequence(s)
    AL596110
    Consensus CDS
    CCDS24822.1
    UniProtKB/Swiss-Prot
    Q60614
    Related
    ENSMUSP00000018644, OTTMUSP00000006053, ENSMUST00000018644, OTTMUST00000013020
    Conserved Domains (1) summary
    pfam00001
    Location:30290
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000077.6 

    Range
    62248984..62266452
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000033.1 

    Range
    68108085..68109506
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
  2. AC_000033.1 

    Range
    69173817..69182904
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)