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dl dorsal [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35047, updated on 6-Jul-2014
Official Symbol
dlprovided by FlyBase
Official Full Name
dorsalprovided by FlyBase
Primary source
FLYBASE:FBgn0260632
Locus tag
Dmel_CG6667
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-EST:GressD7; CG6667; d; dL; Dl; DL; Dmel\CG6667; Dor; Dorsal; fs(2)k10816; GSd447; mat(2)dorsal; NFkappaB
Location:
36C8-36C9; 2-52.9 cM
Exon count :
12
Annotation release Status Assembly Chr Location
Build 5.48 current Release 5 (GCF_000001215.2) 2L NT_033779.4 (17436830..17450360, complement)

Chromosome 2L - NT_033779.4Genomic Context describing neighboring genes Neighboring gene Dorsal-related immunity factor Neighboring gene CG5043 gene product from transcript CG5043-RA Neighboring gene CG33928 gene product from transcript CG33928-RA Neighboring gene CG5050 gene product from transcript CG5050-RA Neighboring gene CG6639 gene product from transcript CG6639-RA Neighboring gene CG18563 gene product from transcript CG18563-RB

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
Toll signaling pathway NAS
Non-traceable Author Statement
more info
 
Toll signaling pathway TAS
Traceable Author Statement
more info
PubMed 
anterior/posterior pattern specification TAS
Traceable Author Statement
more info
PubMed 
defense response NAS
Non-traceable Author Statement
more info
 
defense response TAS
Traceable Author Statement
more info
PubMed 
dorsal/ventral axis specification TAS
Traceable Author Statement
more info
PubMed 
dorsal/ventral pattern formation NAS
Non-traceable Author Statement
more info
PubMed 
ectoderm development NAS
Non-traceable Author Statement
more info
PubMed 
ectodermal cell fate specification TAS
Traceable Author Statement
more info
PubMed 
gastrulation NAS
Non-traceable Author Statement
more info
PubMed 
gastrulation involving germ band extension TAS
Traceable Author Statement
more info
PubMed 
germ cell migration TAS
Traceable Author Statement
more info
PubMed 
heart development NAS
Non-traceable Author Statement
more info
PubMed 
immune response IEP
Inferred from Expression Pattern
more info
PubMed 
immune response NAS
Non-traceable Author Statement
more info
 
immune response TAS
Traceable Author Statement
more info
PubMed 
maternal determination of anterior/posterior axis, embryo IMP
Inferred from Mutant Phenotype
more info
 
melanization defense response IMP
Inferred from Mutant Phenotype
more info
PubMed 
mesoderm development NAS
Non-traceable Author Statement
more info
PubMed 
mesodermal cell fate specification TAS
Traceable Author Statement
more info
PubMed 
negative regulation of gene expression IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of transcription from RNA polymerase II promoter TAS
Traceable Author Statement
more info
PubMed 
negative regulation of transcription, DNA-templated NAS
Non-traceable Author Statement
more info
PubMed 
negative regulation of transcription, DNA-templated TAS
Traceable Author Statement
more info
PubMed 
peripheral nervous system neuron development IMP
Inferred from Mutant Phenotype
more info
PubMed 
plasmatocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter TAS
Traceable Author Statement
more info
PubMed 
positive regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of transcription, DNA-templated TAS
Traceable Author Statement
more info
PubMed 
regulation of alternative mRNA splicing, via spliceosome IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of hemocyte proliferation IDA
Inferred from Direct Assay
more info
PubMed 
regulation of transcription, DNA-templated ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of transcription, DNA-templated NAS
Non-traceable Author Statement
more info
PubMed 
ventral cord development NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm NAS
Non-traceable Author Statement
more info
 
cytoplasm TAS
Traceable Author Statement
more info
PubMed 
neuromuscular junction IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IC
Inferred by Curator
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus NAS
Non-traceable Author Statement
more info
PubMed 
nucleus TAS
Traceable Author Statement
more info
PubMed 
Preferred Names
CG6667 gene product from transcript CG6667-RA
Names
CG6667-PA
CG6667-PB
CG6667-PC
CG6667-PD
CG6667-PE
NFkappabeta
dl-PA
dl-PB
dl-PC
dl-PD
dl-PE
dorsal
embryonic polarity protein dorsal

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.4 

    Range
    17436830..17450360
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_165217.2NP_724052.1  dorsal, isoform A [Drosophila melanogaster]

    See proteins identical to NP_724052.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JHK3
    UniProtKB/Swiss-Prot
    P15330
    Related
    FBpp0080558, FBtr0081005
    Conserved Domains (2) summary
    cd07887
    Location:47220
    Blast Score: 819
    RHD-n_Dorsal_Dif; N-terminal sub-domain of the Rel homology domain (RHD) of the arthropod protein Dorsal
    cd01177
    Location:225326
    Blast Score: 506
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
  2. NM_165218.2NP_724053.1  dorsal, isoform B [Drosophila melanogaster]

    See proteins identical to NP_724053.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JHK3
    UniProtKB/Swiss-Prot
    P15330
    Related
    FBpp0080559, FBtr0081006
    Conserved Domains (2) summary
    cd07887
    Location:47220
    Blast Score: 819
    RHD-n_Dorsal_Dif; N-terminal sub-domain of the Rel homology domain (RHD) of the arthropod protein Dorsal
    cd01177
    Location:225326
    Blast Score: 506
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
  3. NM_001169530.1NP_001163001.1  dorsal, isoform E [Drosophila melanogaster]

    See proteins identical to NP_001163001.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JHK3
    UniProtKB/Swiss-Prot
    P15330
    Related
    FBpp0290598, FBtr0301384
    Conserved Domains (2) summary
    cd07887
    Location:47220
    Blast Score: 819
    RHD-n_Dorsal_Dif; N-terminal sub-domain of the Rel homology domain (RHD) of the arthropod protein Dorsal
    cd01177
    Location:225326
    Blast Score: 506
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
  4. NM_001169529.1NP_001163000.1  dorsal, isoform D [Drosophila melanogaster]

    See proteins identical to NP_001163000.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JHK3
    UniProtKB/Swiss-Prot
    P15330
    Related
    FBpp0290597, FBtr0301383
    Conserved Domains (2) summary
    cd07887
    Location:47220
    Blast Score: 819
    RHD-n_Dorsal_Dif; N-terminal sub-domain of the Rel homology domain (RHD) of the arthropod protein Dorsal
    cd01177
    Location:225326
    Blast Score: 506
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
  5. NM_165219.1NP_724054.1  dorsal, isoform C [Drosophila melanogaster]

    See proteins identical to NP_724054.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    C7LA93
    UniProtKB/Swiss-Prot
    P15330
    Related
    FBpp0080560, FBtr0081007
    Conserved Domains (2) summary
    cd07887
    Location:47220
    Blast Score: 814
    RHD-n_Dorsal_Dif; N-terminal sub-domain of the Rel homology domain (RHD) of the arthropod protein Dorsal
    cd01177
    Location:225326
    Blast Score: 497
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...

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