Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    SRB4 Srb4p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 856743, updated on 5-Jun-2016
    Gene symbol
    SRB4
    Gene description
    Srb4p
    Primary source
    SGD:S000000824
    Locus tag
    YER022W
    Gene type
    protein coding
    RNA name
    Srb4p
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    MED17
    See SRB4 in Map Viewer
    Location:
    chromosome: V
    Exon count:
    1
    Sequence:
    Chromosome: V; NC_001137.3 (198812..200875)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene guanine nucleotide-binding protein subunit alpha Neighboring gene proteasome regulatory particle lid subunit RPN3 Neighboring gene pyrroline-5-carboxylate reductase Neighboring gene carnitine O-acetyltransferase YAT2

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Component Evidence Code Pubs
    core mediator complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    mediator complex IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    Names
    Srb4p
    NP_010939.1
    • Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for basal RNA polymerase II transcription; homozygosity of the human MED17 L371P mutation is associated with infantile cerebral and cerebellar atrophy with poor myelination

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      198812..200875
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178913.1NP_010939.1  Srb4p [Saccharomyces cerevisiae S288c]

      See identical proteins and their annotated locations for NP_010939.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P32569
      Conserved Domains (1) summary
      pfam10156
      Location:84573
      Med17; Subunit 17 of Mediator complex