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    Tgfb1 transforming growth factor, beta 1 [ Mus musculus (house mouse) ]

    Gene ID: 21803, updated on 11-Sep-2016
    Official Symbol
    Tgfb1provided by MGI
    Official Full Name
    transforming growth factor, beta 1provided by MGI
    Primary source
    MGI:MGI:98725
    See related
    Ensembl:ENSMUSG00000002603 Vega:OTTMUSG00000036027
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tgfb; Tgfb-1; TGFbeta1; TGF-beta1
    Summary
    This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. Mice lacking a functional copy of this gene develop severe multifocal inflammatory disease, yolk sac defects and colon cancer. [provided by RefSeq, Aug 2016]
    Orthologs
    Location:
    7 A3; 7 13.98 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (25687002..25705077)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (26472021..26490015)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene transmembrane protein 91 Neighboring gene B9 protein domain 2 Neighboring gene coiled-coil domain containing 97 Neighboring gene heterogeneous nuclear ribonucleoprotein U-like 1

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

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    • Transcriptional regulation of white adipocyte differentiation, organism-specific biosystem (from REACTOME)
      Transcriptional regulation of white adipocyte differentiation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Tuberculosis, organism-specific biosystem (from KEGG)
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    • XPodNet - protein-protein interactions in the podocyte expanded by STRING, organism-specific biosystem (from WikiPathways)
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    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    antigen binding ISO
    Inferred from Sequence Orthology
    more info
     
    cytokine activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    glycoprotein binding ISO
    Inferred from Sequence Orthology
    more info
     
    growth factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein N-terminus binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein heterodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein serine/threonine kinase activator activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transforming growth factor beta receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transforming growth factor beta receptor binding TAS
    Traceable Author Statement
    more info
    PubMed 
    type I transforming growth factor beta receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    type II transforming growth factor beta receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    type II transforming growth factor beta receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    type III transforming growth factor beta receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    ATP biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment TAS
    Traceable Author Statement
    more info
    PubMed 
    MAPK cascade ISO
    Inferred from Sequence Orthology
    more info
     
    Notch signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    SMAD protein complex assembly ISO
    Inferred from Sequence Orthology
    more info
     
    SMAD protein import into nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    SMAD protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    T cell activation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    T cell activation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    T cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    T cell homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    T-helper 17 cell lineage commitment TAS
    Traceable Author Statement
    more info
    PubMed 
    adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains IDA
    Inferred from Direct Assay
    more info
    PubMed 
    animal organ morphogenesis TAS
    Traceable Author Statement
    more info
    PubMed 
    animal organ regeneration ISO
    Inferred from Sequence Orthology
    more info
     
    branch elongation involved in mammary gland duct branching IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell activation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell cycle arrest ISO
    Inferred from Sequence Orthology
    more info
     
    cell growth IEA
    Inferred from Electronic Annotation
    more info
     
    cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    cell proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell proliferation TAS
    Traceable Author Statement
    more info
    PubMed 
    cell-cell junction organization ISO
    Inferred from Sequence Orthology
    more info
     
    cellular calcium ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular response to dexamethasone stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to growth factor stimulus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular response to organic cyclic compound ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to transforming growth factor beta stimulus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular response to transforming growth factor beta stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    chondrocyte differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    common-partner SMAD protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    defense response TAS
    Traceable Author Statement
    more info
    PubMed 
    defense response to fungus, incompatible interaction ISO
    Inferred from Sequence Orthology
    more info
     
    endoderm development IDA
    Inferred from Direct Assay
    more info
    PubMed 
    epidermal growth factor receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    epithelial to mesenchymal transition ISO
    Inferred from Sequence Orthology
    more info
     
    evasion or tolerance of host defenses by virus ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular matrix assembly IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular matrix assembly ISO
    Inferred from Sequence Orthology
    more info
     
    extrinsic apoptotic signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    face morphogenesis IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    germ cell migration IDA
    Inferred from Direct Assay
    more info
    PubMed 
    growth IEA
    Inferred from Electronic Annotation
    more info
     
    hematopoietic progenitor cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    hyaluronan catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    inflammatory response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    inflammatory response ISO
    Inferred from Sequence Orthology
    more info
     
    lens fiber cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    lipopolysaccharide-mediated signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    lymph node development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mammary gland branching involved in thelarche IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mammary gland development IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitotic cell cycle checkpoint ISO
    Inferred from Sequence Orthology
    more info
     
    mononuclear cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    morphogenesis of a branching structure ISO
    Inferred from Sequence Orthology
    more info
     
    myelination ISO
    Inferred from Sequence Orthology
    more info
     
    myeloid dendritic cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of DNA replication ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of T cell activation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of T cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of blood vessel endothelial cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cell growth IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of cell growth ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cell proliferation TAS
    Traceable Author Statement
    more info
    PubMed 
    negative regulation of cell-cell adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of epithelial cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of fat cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of gene silencing by miRNA ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of hyaluronan biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of immune response ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of interleukin-17 production IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of macrophage cytokine production ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of myoblast differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of neuroblast proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of ossification IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of phagocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of production of miRNAs involved in gene silencing by miRNA ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of protein localization to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of release of sequestered calcium ion into cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of skeletal muscle tissue development ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription from RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of transcription from RNA polymerase II promoter IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    negative regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    oligodendrocyte development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    pathway-restricted SMAD protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    pathway-restricted SMAD protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    phosphate-containing compound metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of MAP kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of NAD+ ADP-ribosyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of NF-kappaB transcription factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of SMAD protein import into nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of blood vessel endothelial cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of branching involved in ureteric bud morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cardiac muscle cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cell cycle arrest IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of cell division IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cell proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cellular protein metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of chemotaxis ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of collagen biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of collagen biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of epithelial cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of epithelial to mesenchymal transition IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of epithelial to mesenchymal transition ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of exit from mitosis ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of fibroblast migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of fibroblast migration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of fibroblast proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of gene expression IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of histone acetylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of histone deacetylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of interleukin-17 production IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of interleukin-17 production ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of isotype switching to IgA isotypes ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of mononuclear cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of odontogenesis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of pathway-restricted SMAD protein phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    positive regulation of pathway-restricted SMAD protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of peptidyl-serine phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of peptidyl-threonine phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of peptidyl-tyrosine phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of phosphatidylinositol 3-kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of pri-miRNA transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein complex assembly ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein dephosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein import into nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein kinase B signaling ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein localization to nucleus IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein secretion ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of receptor clustering IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of regulatory T cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of smooth muscle cell differentiation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of superoxide anion generation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription from RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of transcription from RNA polymerase II promoter IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription regulatory region DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of vascular permeability ISO
    Inferred from Sequence Orthology
    more info
     
    protein export from nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    protein import into nucleus, translocation ISO
    Inferred from Sequence Orthology
    more info
     
    protein kinase B signaling ISO
    Inferred from Sequence Orthology
    more info
     
    protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein phosphorylation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    receptor catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation TAS
    Traceable Author Statement
    more info
    PubMed 
    regulation of DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of MAPK cascade IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    regulation of SMAD protein import into nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of actin cytoskeleton reorganization IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    regulation of binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of branching involved in mammary gland duct morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of cartilage development IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of cell proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT regulation of epithelial to mesenchymal transition involved in endocardial cushion formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of gene expression IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of interleukin-23 production IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of protein import into nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of regulatory T cell differentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of sodium ion transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of striated muscle tissue development IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of transforming growth factor beta receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    regulatory T cell differentiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulatory T cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to cholesterol ISO
    Inferred from Sequence Orthology
    more info
     
    response to estradiol ISO
    Inferred from Sequence Orthology
    more info
     
    response to organic substance ISO
    Inferred from Sequence Orthology
    more info
     
    response to progesterone ISO
    Inferred from Sequence Orthology
    more info
     
    skeletal muscle tissue development TAS
    Traceable Author Statement
    more info
    PubMed 
    skeletal system development TAS
    Traceable Author Statement
    more info
    PubMed 
    tolerance induction to self antigen IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transforming growth factor beta receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transforming growth factor beta receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    ureteric bud development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    wound healing ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    axon ISO
    Inferred from Sequence Orthology
    more info
     
    blood microparticle ISO
    Inferred from Sequence Orthology
    more info
     
    cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular matrix ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with microvillus ISO
    Inferred from Sequence Orthology
    more info
     
    neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    proteinaceous extracellular matrix IDA
    Inferred from Direct Assay
    more info
    PubMed 
    secretory granule ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    transforming growth factor beta-1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011577.2NP_035707.1  transforming growth factor beta-1 preproprotein

      See identical proteins and their annotated locations for NP_035707.1

      Status: REVIEWED

      Source sequence(s)
      AA510019, AA821506, AC162614, BQ030974, CK625059
      Consensus CDS
      CCDS20993.1
      UniProtKB/Swiss-Prot
      P04202
      UniProtKB/TrEMBL
      Q3UNK5
      Related
      ENSMUSP00000002678, OTTMUSP00000051111, ENSMUST00000002678, OTTMUST00000092468
      Conserved Domains (2) summary
      smart00204
      Location:293390
      TGFB; Transforming growth factor-beta (TGF-beta) family
      pfam00688
      Location:29261
      TGFb_propeptide; TGF-beta propeptide

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      25687002..25705077
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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