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    Zfx zinc finger protein X-linked [ Mus musculus (house mouse) ]

    Gene ID: 22764, updated on 8-Aug-2016
    Official Symbol
    Zfxprovided by MGI
    Official Full Name
    zinc finger protein X-linkedprovided by MGI
    Primary source
    MGI:MGI:99211
    See related
    Ensembl:ENSMUSG00000079509 Vega:OTTMUSG00000018032
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Zfx5; Zfx6; Zfx5,6
    Orthologs
    Location:
    X 41.48 cM; X D
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) X NC_000086.7 (94074631..94150645, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (91319970..91368746, complement)

    Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene predicted gene 15165 Neighboring gene predicted pseudogene 6987 Neighboring gene uncharacterized LOC108168488 Neighboring gene eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked Neighboring gene kelch-like 15 Neighboring gene microRNA 7673

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • PluriNetWork, organism-specific biosystem (from WikiPathways)
      PluriNetWork, organism-specific biosystemThe aim of the PluriNetWork is to give an overview of specific mechanisms associated with pluripotency in mouse. Each node represents a gene and its corresponding protein product. As stated, we inten...

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    RNA polymerase II regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    transcription factor activity, sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    embryo development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    fertilization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    germ cell development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    homeostasis of number of cells IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organism growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    oocyte development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ovarian follicle development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    parental behavior IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    post-embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    spermatogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    zinc finger X-chromosomal protein
    Names
    X-linked zinc finger protein
    zinc finger protein X-linked 5
    zinc finger protein X-linked 6

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044386.1NP_001037851.1  zinc finger X-chromosomal protein

      See identical proteins and their annotated locations for NP_001037851.1

      Status: VALIDATED

      Source sequence(s)
      AL626786, BF022794, M32308
      Consensus CDS
      CCDS30276.1
      UniProtKB/Swiss-Prot
      P17012
      UniProtKB/TrEMBL
      B1ASD1
      Related
      ENSMUSP00000085423, OTTMUSP00000019571, ENSMUST00000088102, OTTMUST00000043537
      Conserved Domains (5) summary
      COG5048
      Location:537674
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:484504
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:713735
      zf-C2H2; Zinc finger, C2H2 type
      pfam04704
      Location:71404
      Zfx_Zfy_act; Zfx / Zfy transcription activation region
      pfam13465
      Location:556578
      zf-H2C2_2; Zinc-finger double domain
    2. NM_011768.2NP_035898.2  zinc finger X-chromosomal protein

      See identical proteins and their annotated locations for NP_035898.2

      Status: VALIDATED

      Source sequence(s)
      AL626786, BF022794, CJ133771, CJ195389, CN460698
      Consensus CDS
      CCDS30276.1
      UniProtKB/Swiss-Prot
      P17012
      UniProtKB/TrEMBL
      B1ASD1
      Related
      ENSMUSP00000109560, ENSMUST00000113927
      Conserved Domains (5) summary
      COG5048
      Location:537674
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:484504
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:713735
      zf-C2H2; Zinc finger, C2H2 type
      pfam04704
      Location:71404
      Zfx_Zfy_act; Zfx / Zfy transcription activation region
      pfam13465
      Location:556578
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000086.7 Reference GRCm38.p4 C57BL/6J

      Range
      94074631..94150645 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527967.3XP_006528030.1  

      Conserved Domains (5) summary
      pfam04704
      Location:103387
      Zfx_Zfy_act; Zfx / Zfy transcription activation region
      COG5048
      Location:520644
      COG5048; FOG: Zn-finger [General function prediction only]
      pfam13465
      Location:539561
      zf-H2C2_2; Zinc-finger double domain
      cl19880
      Location:404424
      ROS_MUCR; ROS/MUCR transcriptional regulator protein
      sd00017
      Location:467487
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. XM_006527965.3XP_006528028.1  

      Conserved Domains (5) summary
      pfam04704
      Location:103437
      Zfx_Zfy_act; Zfx / Zfy transcription activation region
      COG5048
      Location:570832
      COG5048; FOG: Zn-finger [General function prediction only]
      pfam13465
      Location:589611
      zf-H2C2_2; Zinc-finger double domain
      cl19880
      Location:454474
      ROS_MUCR; ROS/MUCR transcriptional regulator protein
      sd00017
      Location:517537
      ZF_C2H2; C2H2 Zn finger [structural motif]
    3. XM_017318465.1XP_017173954.1  

      Conserved Domains (5) summary
      COG5048
      Location:487624
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:434454
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:663685
      zf-C2H2; Zinc finger, C2H2 type
      pfam04704
      Location:71354
      Zfx_Zfy_act; Zfx / Zfy transcription activation region
      pfam13465
      Location:506528
      zf-H2C2_2; Zinc-finger double domain
    4. XM_017318466.1XP_017173955.1  

      Conserved Domains (5) summary
      COG5048
      Location:487624
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:434454
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:663685
      zf-C2H2; Zinc finger, C2H2 type
      pfam04704
      Location:71354
      Zfx_Zfy_act; Zfx / Zfy transcription activation region
      pfam13465
      Location:506528
      zf-H2C2_2; Zinc-finger double domain
    5. XM_006527966.3XP_006528029.1  

      See identical proteins and their annotated locations for XP_006528029.1

      UniProtKB/Swiss-Prot
      P17012
      UniProtKB/TrEMBL
      B1ASD1
      Conserved Domains (5) summary
      COG5048
      Location:537674
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:484504
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:713735
      zf-C2H2; Zinc finger, C2H2 type
      pfam04704
      Location:71404
      Zfx_Zfy_act; Zfx / Zfy transcription activation region
      pfam13465
      Location:556578
      zf-H2C2_2; Zinc-finger double domain
    6. XM_017318464.1XP_017173953.1  

      Conserved Domains (5) summary
      COG5048
      Location:487624
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:434454
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:663685
      zf-C2H2; Zinc finger, C2H2 type
      pfam04704
      Location:71354
      Zfx_Zfy_act; Zfx / Zfy transcription activation region
      pfam13465
      Location:506528
      zf-H2C2_2; Zinc-finger double domain
    7. XM_011247577.2XP_011245879.1  

      See identical proteins and their annotated locations for XP_011245879.1

      UniProtKB/Swiss-Prot
      P17012
      UniProtKB/TrEMBL
      B1ASD1
      Conserved Domains (5) summary
      COG5048
      Location:537674
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:484504
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:713735
      zf-C2H2; Zinc finger, C2H2 type
      pfam04704
      Location:71404
      Zfx_Zfy_act; Zfx / Zfy transcription activation region
      pfam13465
      Location:556578
      zf-H2C2_2; Zinc-finger double domain
    8. XM_011247578.2XP_011245880.1  

      See identical proteins and their annotated locations for XP_011245880.1

      UniProtKB/Swiss-Prot
      P17012
      UniProtKB/TrEMBL
      B1ASD1
      Conserved Domains (5) summary
      COG5048
      Location:537674
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:484504
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:713735
      zf-C2H2; Zinc finger, C2H2 type
      pfam04704
      Location:71404
      Zfx_Zfy_act; Zfx / Zfy transcription activation region
      pfam13465
      Location:556578
      zf-H2C2_2; Zinc-finger double domain