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Chd2 chromodomain helicase DNA binding protein 2 [ Mus musculus (house mouse) ]

Gene ID: 244059, updated on 16-Dec-2014
Official Symbol
Chd2provided by MGI
Official Full Name
chromodomain helicase DNA binding protein 2provided by MGI
Primary source
MGI:MGI:2448567
See related
Ensembl:ENSMUSG00000078671; Vega:OTTMUSG00000036993
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CHD-2; AI851092; BC029703; 2810013C04Rik; 2810040A01Rik; 5630401D06Rik
See Chd2 in Epigenomics, MapViewer
Location:
7 D1; 7
Exon count:
39
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 7 NC_000073.6 (73426652..73541746, complement)

Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA A730056A06 gene Neighboring gene uncharacterized LOC100505025 Neighboring gene repulsive guidance molecule family member A Neighboring gene RIKEN cDNA 1810026B05 gene Neighboring gene predicted gene, 30149 Neighboring gene Smad nuclear interacting protein 1 pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
DNA binding IEA
Inferred from Electronic Annotation
more info
 
core promoter sequence-specific DNA binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
helicase activity IEA
Inferred from Electronic Annotation
more info
 
histone binding IDA
Inferred from Direct Assay
more info
PubMed 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cellular response to DNA damage stimulus IMP
Inferred from Mutant Phenotype
more info
PubMed 
chromatin modification IEA
Inferred from Electronic Annotation
more info
 
hematopoietic stem cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
muscle organ development IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
nucleolus ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
chromodomain-helicase-DNA-binding protein 2
Names
chromodomain-helicase-DNA-binding protein 2
ATP-dependent helicase CHD2
NP_001074814.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081345.2NP_001074814.2  chromodomain-helicase-DNA-binding protein 2

    See proteins identical to NP_001074814.2

    Status: VALIDATED

    Source sequence(s)
    AC099699, AC154883
    Consensus CDS
    CCDS52274.1
    UniProtKB/Swiss-Prot
    E9PZM4
    Related
    ENSMUSP00000126352, OTTMUSP00000053039, ENSMUST00000169922, OTTMUST00000095121
    Conserved Domains (5) summary
    pfam13907
    Location:14681555
    DUF4208; Domain of unknown function (DUF4208)
    cd00024
    Location:282344
    CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
    cd00046
    Location:503648
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:789913
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00176
    Location:487768
    SNF2_N; SNF2 family N-terminal domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000073.6 

    Range
    73426652..73541746
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000029.1 

    Range
    70874423..70989778
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)