Display Settings:

Format

Send to:

Choose Destination

Pde6b phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide [ Mus musculus (house mouse) ]

Gene ID: 18587, updated on 20-Jan-2015
Official Symbol
Pde6bprovided by MGI
Official Full Name
phosphodiesterase 6B, cGMP, rod receptor, beta polypeptideprovided by MGI
Primary source
MGI:MGI:97525
See related
Ensembl:ENSMUSG00000029491; Vega:OTTMUSG00000026326
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
r; rd; rd1; Pdeb; rd-1; rd10
Orthologs
See Pde6b in MapViewer
Location:
5 F; 5 53.07 cM
Exon count:
22
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 5 NC_000071.6 (108388373..108431743)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene down-regulator of transcription 1 Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class G Neighboring gene predicted gene, 34254 Neighboring gene predicted gene, 34204 Neighboring gene predicted gene, 34319 Neighboring gene ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit E

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Markers

Homology

Clone Names

  • MGC150321

Gene Ontology Provided by MGI

Function Evidence Code Pubs
3',5'-cyclic-GMP phosphodiesterase activity ISO
Inferred from Sequence Orthology
more info
 
3',5'-cyclic-nucleotide phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
phosphoric diester hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
GMP metabolic process ISO
Inferred from Sequence Orthology
more info
 
cytosolic calcium ion homeostasis ISO
Inferred from Sequence Orthology
more info
 
detection of light stimulus IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to stimulus IEA
Inferred from Electronic Annotation
more info
 
retina development in camera-type eye IMP
Inferred from Mutant Phenotype
more info
PubMed 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
visual perception IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cell ISO
Inferred from Sequence Orthology
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
photoreceptor outer segment IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
Names
rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
GMP-PDE beta
retinal degeneration 1
cGMP-phosphodiesterase beta-subunit
phosphodiesterase, cGMP, rod receptor, beta polypeptide
NP_032832.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008806.2NP_032832.2  rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta precursor

    See proteins identical to NP_032832.2

    Status: VALIDATED

    Source sequence(s)
    AK044364, BE944318, BU505563
    Consensus CDS
    CCDS19510.1
    UniProtKB/Swiss-Prot
    P23440
    Related
    ENSMUSP00000031456, OTTMUSP00000032409, ENSMUST00000031456, OTTMUST00000065111
    Conserved Domains (3) summary
    pfam00233
    Location:556804
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    smart00065
    Location:71230
    GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
    cd00077
    Location:556741
    HDc; Metal dependent phosphohydrolases with conserved 'HD' motif

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000071.6 

    Range
    108388373..108431743
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000027.1 

    Range
    105508147..105551677
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)