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    TCF3 transcription factor 3 [ Gallus gallus (chicken) ]

    Gene ID: 395146, updated on 26-May-2016
    Symbol
    TCF3provided by CGNC
    Full Name
    transcription factor 3provided by CGNC
    Primary source
    CGNC:739
    See related
    Ensembl:ENSGALG00000001093
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    G12
    Orthologs
    Location:
    chromosome: 28
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    103 current Gallus_gallus-5.0 (GCF_000002315.4) 28 NC_006115.4 (2386180..2445344)
    102 previous assembly Gallus_gallus-4.0 (GCF_000002315.3) 28 NC_006115.3 (2315136..2365833)

    Chromosome 28 - NC_006115.4Genomic Context describing neighboring genes Neighboring gene ATPase, aminophospholipid transporter, class I, type 8B, member 3 Neighboring gene one cut homeobox 1 Neighboring gene uncharacterized LOC107055356 Neighboring gene ubiquinol-cytochrome c reductase, complex III subunit XI Neighboring gene methyl-CpG binding domain protein 3

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • Delta-Notch Signaling Pathway, organism-specific biosystem (from WikiPathways)
      Delta-Notch Signaling Pathway, organism-specific biosystemThere are 4 Notch receptors in humans (Notch 1-4) that bind to a family of 5 ligands (Jagged 1 and 2 and Delta-like 1-3). The Notch receptors are expressed on the cell surface as heterodimeric protei...
    • Id Signaling Pathway, organism-specific biosystem (from WikiPathways)
      Id Signaling Pathway, organism-specific biosystemInhibitor of DNA binding (ID) proteins are members of the helix-loop-helix (HLH) family of proteins which lack a DNA binding domain themselves but bind to other family members inhibiting their DNA bi...

    Homology

    Preferred Names
    transcription factor E2-alpha
    Names
    class A basic helix-loop-helix transcription factor G12
    helix-loop-helix protein E12
    helix-loop-helix protein E47
    transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_204486.2NP_989817.2  transcription factor E2-alpha

      See identical proteins and their annotated locations for NP_989817.2

      Status: PROVISIONAL

      Source sequence(s)
      AJ579995
      UniProtKB/TrEMBL
      Q70IK3
      Related
      ENSGALP00000001635, ENSGALT00000001637
      Conserved Domains (3) summary
      cd00083
      Location:562622
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam09184
      Location:458564
      PPP4R2; PPP4R2
      cl07029
      Location:515573
      SPT2; SPT2 chromatin protein

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 103 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Gallus_gallus-5.0 Primary Assembly

    Genomic

    1. NC_006115.4 Reference Gallus_gallus-5.0 Primary Assembly

      Range
      2386180..2445344
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015299909.1XP_015155395.1  

      Conserved Domains (1) summary
      cd00083
      Location:597657
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    2. XM_015299889.1XP_015155375.1  

      Conserved Domains (2) summary
      cd00083
      Location:597657
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam08703
      Location:544674
      PLC-beta_C; PLC-beta C terminal
    3. XM_015299890.1XP_015155376.1  

      Conserved Domains (2) summary
      cd00083
      Location:596656
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam08703
      Location:543673
      PLC-beta_C; PLC-beta C terminal
    4. XM_015299891.1XP_015155377.1  

      Conserved Domains (2) summary
      cd00083
      Location:596656
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam08703
      Location:543673
      PLC-beta_C; PLC-beta C terminal
    5. XM_015299894.1XP_015155380.1  

      Conserved Domains (3) summary
      cd00083
      Location:592652
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam09184
      Location:488594
      PPP4R2; PPP4R2
      cl07029
      Location:545603
      SPT2; SPT2 chromatin protein
    6. XM_015299892.1XP_015155378.1  

      Conserved Domains (2) summary
      cd00083
      Location:593653
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam08703
      Location:544670
      PLC-beta_C; PLC-beta C terminal
    7. XM_015299895.1XP_015155381.1  

      Conserved Domains (2) summary
      cd00083
      Location:592652
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam08703
      Location:544669
      PLC-beta_C; PLC-beta C terminal
    8. XM_015299900.1XP_015155386.1  

      Conserved Domains (1) summary
      cd00083
      Location:567627
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    9. XM_015299901.1XP_015155387.1  

      Conserved Domains (1) summary
      cd00083
      Location:566626
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    10. XM_015299902.1XP_015155388.1  

      Conserved Domains (1) summary
      cd00083
      Location:566626
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    11. XM_015299903.1XP_015155389.1  

      Conserved Domains (1) summary
      cd00083
      Location:565625
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    12. XM_015299896.1XP_015155382.1  

      Conserved Domains (2) summary
      cd00083
      Location:588648
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam08703
      Location:544665
      PLC-beta_C; PLC-beta C terminal
    13. XM_015299897.1XP_015155383.1  

      Conserved Domains (1) summary
      cd00083
      Location:587647
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    14. XM_015299910.1XP_015155396.1  

      Conserved Domains (3) summary
      cd00083
      Location:561621
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam09184
      Location:457563
      PPP4R2; PPP4R2
      cl07029
      Location:514572
      SPT2; SPT2 chromatin protein
    15. XM_015299911.1XP_015155397.1  

      Conserved Domains (3) summary
      cd00083
      Location:560620
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam09184
      Location:456562
      PPP4R2; PPP4R2
      cl07029
      Location:513571
      SPT2; SPT2 chromatin protein
    16. XM_015299906.1XP_015155392.1  

      Conserved Domains (1) summary
      cd00083
      Location:557617
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    17. XM_015299905.1XP_015155391.1  

      UniProtKB/TrEMBL
      Q70IK2
      Conserved Domains (2) summary
      cd00083
      Location:558618
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam08703
      Location:514635
      PLC-beta_C; PLC-beta C terminal
    18. XM_015299912.1XP_015155398.1  

      Conserved Domains (2) summary
      cd00083
      Location:557617
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam08703
      Location:513634
      PLC-beta_C; PLC-beta C terminal
    19. XM_015299913.1XP_015155399.1  

      Conserved Domains (2) summary
      cd00083
      Location:556616
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam08703
      Location:512633
      PLC-beta_C; PLC-beta C terminal
    20. XM_015299914.1XP_015155400.1  

      Conserved Domains (1) summary
      cd00083
      Location:555615
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    21. XM_015299907.1XP_015155393.1  

      Conserved Domains (1) summary
      cd00083
      Location:557617
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    22. XM_015299908.1XP_015155394.1  

      Conserved Domains (1) summary
      cd00083
      Location:556616
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    23. XM_015299898.1XP_015155384.1  

      Conserved Domains (1) summary
      cd00083
      Location:566626
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    24. XM_015299899.1XP_015155385.1  

      Conserved Domains (1) summary
      cd00083
      Location:565625
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...

    RNA

    1. XR_001470413.1 RNA Sequence

    2. XR_001470414.1 RNA Sequence