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Fmn2 formin 2 [ Mus musculus (house mouse) ]

Gene ID: 54418, updated on 19-Jul-2014
Official Symbol
Fmn2provided by MGI
Official Full Name
formin 2provided by MGI
Primary source
MGI:1859252
See related
Ensembl:ENSMUSG00000028354
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AU024104
See Fmn2 in Epigenomics, MapViewer
Location:
1 H3; 1 81.04 cM
Exon count :
18
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 1 NC_000067.6 (174501825..174822729)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene olfactory receptor 414 Neighboring gene olfactory receptor 220 Neighboring gene uncharacterized LOC102640096 Neighboring gene lines homolog 2 pseudogene Neighboring gene gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis) Neighboring gene regulator of G protein signaling 7

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
actin binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
actin filament bundle assembly IMP
Inferred from Mutant Phenotype
more info
 
actin nucleation IEA
Inferred from Electronic Annotation
more info
 
cellular response to DNA damage stimulus ISO
Inferred from Sequence Orthology
more info
 
cellular response to hypoxia ISO
Inferred from Sequence Orthology
more info
 
establishment of meiotic spindle localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
formin-nucleated actin cable assembly IMP
Inferred from Mutant Phenotype
more info
 
homologous chromosome movement towards spindle pole involved in homologous chromosome segregation IMP
Inferred from Mutant Phenotype
more info
PubMed 
intracellular transport IMP
Inferred from Mutant Phenotype
more info
 
meiotic chromosome movement towards spindle pole IMP
Inferred from Mutant Phenotype
more info
 
multicellular organismal development IEA
Inferred from Electronic Annotation
more info
 
negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
oogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
polar body extrusion after meiotic divisions IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein transport IEA
Inferred from Electronic Annotation
more info
 
response to stress IEA
Inferred from Electronic Annotation
more info
 
transport IEA
Inferred from Electronic Annotation
more info
 
vesicle-mediated transport IMP
Inferred from Mutant Phenotype
more info
 
Component Evidence Code Pubs
colocalizes_with actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
actin filament IEA
Inferred from Electronic Annotation
more info
 
cell IMP
Inferred from Mutant Phenotype
more info
 
cell cortex IDA
Inferred from Direct Assay
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic vesicle membrane IDA
Inferred from Direct Assay
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 
endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
 
intracellular IMP
Inferred from Mutant Phenotype
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
microvillus IDA
Inferred from Direct Assay
more info
 
nucleolus ISO
Inferred from Sequence Orthology
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
spindle IDA
Inferred from Direct Assay
more info
 

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019445.2NP_062318.2  formin-2

    See proteins identical to NP_062318.2

    Status: VALIDATED

    Source sequence(s)
    BC094606, BM228488, BP758042
    Consensus CDS
    CCDS48459.1
    UniProtKB/Swiss-Prot
    Q9JL04
    Related
    ENSMUSP00000030039, ENSMUST00000030039
    Conserved Domains (1) summary
    pfam02181
    Location:11391529
    Blast Score: 963
    FH2; Formin Homology 2 Domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000067.6 

    Range
    174501825..174822729
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000023.1 

    Range
    181581367..181911120
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

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