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Ace Acetylcholine esterase [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41625, updated on 6-Jul-2014
Official Symbol
Aceprovided by FlyBase
Official Full Name
Acetylcholine esteraseprovided by FlyBase
Primary source
FLYBASE:FBgn0000024
Locus tag
Dmel_CG17907
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
AcChE; ace; ACE; ace-2; ache; AchE; AChE; CG17907; CHE; dAChE; dmAChE; DmAChE; Dmel\CG17907; FBgn0000024; l(3)26; l(3)87Ed
Location:
87E2-87E3; 3-52.5 cM
Exon count :
12
Annotation release Status Assembly Chr Location
Build 5.48 current Release 5 (GCF_000001215.2) 3R NT_033777.2 (9048673..9085239, complement)

Chromosome 3R - NT_033777.2Genomic Context describing neighboring genes Neighboring gene CG8483 gene product from transcript CG8483-RA Neighboring gene CG8476 gene product from transcript CG8476-RA Neighboring gene CG11686 gene product from transcript CG11686-RB Neighboring gene CG15889 gene product from transcript CG15889-RA

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
acetylcholinesterase activity IDA
Inferred from Direct Assay
more info
PubMed 
acetylcholinesterase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
acetylcholinesterase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
acetylcholinesterase activity NAS
Non-traceable Author Statement
more info
 
carboxylic ester hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
cholinesterase activity IDA
Inferred from Direct Assay
more info
PubMed 
cholinesterase activity NAS
Non-traceable Author Statement
more info
 
protein homodimerization activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
acetylcholine catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
acetylcholine catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
acetylcholine catabolic process NAS
Non-traceable Author Statement
more info
 
acetylcholine catabolic process in synaptic cleft IEA
Inferred from Electronic Annotation
more info
 
choline catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
phototaxis IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to carbamate NAS
Non-traceable Author Statement
more info
 
response to organophosphorus NAS
Non-traceable Author Statement
more info
 
synaptic transmission IMP
Inferred from Mutant Phenotype
more info
PubMed 
synaptic transmission, cholinergic IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
membrane NAS
Non-traceable Author Statement
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
synapse NAS
Non-traceable Author Statement
more info
 
Preferred Names
CG17907 gene product from transcript CG17907-RC
Names
Ace-PA
Ace-PB
Ace-PC
CG17907-PA
CG17907-PB
CG17907-PC
acetyl choline esterase
acetylcholine esterase
acetylcholinesterase
NP_001163600.1
NP_001262530.1
NP_476953.1

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.2 

    Range
    9048673..9085239
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275601.1NP_001262530.1  acetylcholine esterase, isoform C [Drosophila melanogaster]

    See proteins identical to NP_001262530.1

    Status: REVIEWED

    Conserved Domains (1) summary
    pfam00135
    Location:41601
    Blast Score: 1427
    COesterase; Carboxylesterase family
  2. NM_057605.5NP_476953.1  acetylcholine esterase, isoform A [Drosophila melanogaster]

    See proteins identical to NP_476953.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JIJ8
    UniProtKB/Swiss-Prot
    P07140
    Related
    FBpp0082248, FBtr0082780
    Conserved Domains (1) summary
    pfam00135
    Location:41601
    Blast Score: 1431
    COesterase; Carboxylesterase family
  3. NM_001170129.2NP_001163600.1  acetylcholine esterase, isoform B [Drosophila melanogaster]

    See proteins identical to NP_001163600.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JIJ8
    UniProtKB/Swiss-Prot
    P07140
    Related
    FBpp0289713, FBtr0300486
    Conserved Domains (1) summary
    pfam00135
    Location:41601
    Blast Score: 1431
    COesterase; Carboxylesterase family

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