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Mr1 major histocompatibility complex, class I-related [ Mus musculus (house mouse) ]

Gene ID: 15064, updated on 20-Feb-2015
Official Symbol
Mr1provided by MGI
Official Full Name
major histocompatibility complex, class I-relatedprovided by MGI
Primary source
MGI:MGI:1195463
See related
Ensembl:ENSMUSG00000026471; Vega:OTTMUSG00000049823
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
H2ls
Orthologs
See Mr1 in MapViewer
Location:
1; 1 H1
Exon count:
6
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 1 NC_000067.6 (155127872..155146813, complement)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105246739 Neighboring gene immediate early response 5 Neighboring gene predicted gene, 30922 Neighboring gene syntaxin 6 Neighboring gene high mobility group protein B3 pseudogene Neighboring gene cDNA sequence BC034090 Neighboring gene predicted gene, 31102

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
antigen binding IBA
Inferred from Biological aspect of Ancestor
more info
 
peptide antigen binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
antigen processing and presentation IBA
Inferred from Biological aspect of Ancestor
more info
 
antigen processing and presentation of peptide antigen via MHC class I IEA
Inferred from Electronic Annotation
more info
 
cytokine production involved in immune response IMP
Inferred from Mutant Phenotype
more info
PubMed 
defense response to Gram-negative bacterium IMP
Inferred from Mutant Phenotype
more info
PubMed 
immune response IEA
Inferred from Electronic Annotation
more info
 
immune system process IEA
Inferred from Electronic Annotation
more info
 
innate immune response IEA
Inferred from Electronic Annotation
more info
 
interleukin-1 beta production IMP
Inferred from Mutant Phenotype
more info
PubMed 
interleukin-17 production IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of T cell mediated cytotoxicity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
MHC class I protein complex IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
major histocompatibility complex class I-related gene protein
Names
major histocompatibility complex class I-related gene protein
MCH class I
MHC class I-related gene protein
MHC class-I related-gene protein
class I histocompatibility antigen-like protein
histocompatibility-2 complex class 1-like sequence

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008209.4NP_032235.1  major histocompatibility complex class I-related gene protein precursor

    See proteins identical to NP_032235.1

    Status: PROVISIONAL

    Source sequence(s)
    AC140038
    Consensus CDS
    CCDS15383.1
    UniProtKB/Swiss-Prot
    Q8HWB0
    Related
    ENSMUSP00000027744, OTTMUSP00000068579, ENSMUST00000027744, OTTMUST00000126883
    Conserved Domains (2) summary
    cd07698
    Location:198288
    IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
    cl08246
    Location:21194
    MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000067.6 Reference GRCm38.p3 C57BL/6J

    Range
    155127872..155146813
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006529144.2XP_006529207.1  

    See proteins identical to XP_006529207.1

    UniProtKB/Swiss-Prot
    Q8HWB0
    Conserved Domains (2) summary
    cd07698
    Location:86176
    IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
    cl08246
    Location:182
    MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2
  2. XM_006529143.2XP_006529206.1  

    Conserved Domains (2) summary
    cd07698
    Location:127217
    IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
    cl08246
    Location:35123
    MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2

Alternate Mm_Celera

Genomic

  1. AC_000023.1 Alternate Mm_Celera

    Range
    157557055..157575953
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)