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    Arsa arylsulfatase A [ Mus musculus (house mouse) ]

    Gene ID: 11883, updated on 24-Jun-2016
    Official Symbol
    Arsaprovided by MGI
    Official Full Name
    arylsulfatase Aprovided by MGI
    Primary source
    MGI:MGI:88077
    See related
    Ensembl:ENSMUSG00000022620 Vega:OTTMUSG00000035225
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ASA; As2; AS-A; As-2; TISP73; AW212749
    Orthologs
    Location:
    15; 15 E
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 15 NC_000081.6 (89472476..89477424, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (89302907..89307855, complement)

    Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105246016 Neighboring gene mitogen-activated protein kinase 8 interacting protein 2 Neighboring gene RIKEN cDNA C230037L18 gene Neighboring gene predicted gene, 41381 Neighboring gene uncharacterized LOC105246018 Neighboring gene SH3/ankyrin domain gene 3

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    arylsulfatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    calcium ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    cerebroside-sulfatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    sulfuric ester hydrolase activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    autophagy ISO
    Inferred from Sequence Orthology
    more info
     
    binding of sperm to zona pellucida IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    central nervous system development ISO
    Inferred from Sequence Orthology
    more info
     
    metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    response to estrogen ISO
    Inferred from Sequence Orthology
    more info
     
    response to ethanol ISO
    Inferred from Sequence Orthology
    more info
     
    response to methylmercury ISO
    Inferred from Sequence Orthology
    more info
     
    response to nutrient ISO
    Inferred from Sequence Orthology
    more info
     
    response to pH ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    acrosomal vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    endosome ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    extrinsic component of external side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    lysosome ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    arylsulfatase A
    Names
    cerebroside-sulfatase
    NP_033843.2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009713.4NP_033843.2  arylsulfatase A precursor

      See identical proteins and their annotated locations for NP_033843.2

      Status: VALIDATED

      Source sequence(s)
      AC137513
      Consensus CDS
      CCDS27753.1
      UniProtKB/Swiss-Prot
      P50428
      Related
      ENSMUSP00000127646, OTTMUSP00000049092, ENSMUST00000165199, OTTMUST00000089775
      Conserved Domains (3) summary
      COG3119
      Location:16440
      AslA; Arylsulfatase A or related enzyme [Inorganic ion transport and metabolism]
      pfam00884
      Location:20345
      Sulfatase; Sulfatase
      pfam14707
      Location:367501
      Sulfatase_C; C-terminal region of aryl-sulfatase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000081.6 Reference GRCm38.p4 C57BL/6J

      Range
      89472476..89477424 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)