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    Tnfsf15 tumor necrosis factor (ligand) superfamily, member 15 [ Mus musculus (house mouse) ]

    Gene ID: 326623, updated on 24-Jun-2016
    Official Symbol
    Tnfsf15provided by MGI
    Official Full Name
    tumor necrosis factor (ligand) superfamily, member 15provided by MGI
    Primary source
    MGI:MGI:2180140
    See related
    Ensembl:ENSMUSG00000050395 Vega:OTTMUSG00000000303
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tl1; Tl1a; Vegi; Tnlg1b
    Orthologs
    Location:
    4; 4 C1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (63724603..63745113, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (63385637..63406147, complement)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene predicted gene 11482 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene, 42295 Neighboring gene predicted gene, 42294 Neighboring gene tumor necrosis factor (ligand) superfamily, member 8 Neighboring gene ribosomal protein L17, pseudogene 4

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    cytokine activity IEA
    Inferred from Electronic Annotation
    more info
     
    death receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    tumor necrosis factor receptor binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    activation of NF-kappaB-inducing kinase activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    activation of cysteine-type endopeptidase activity involved in apoptotic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cytokine metabolic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    immune response IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of cytokine secretion ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    extracellular space IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Preferred Names
    tumor necrosis factor ligand superfamily member 15
    Names
    TNF ligand-related molecule 1
    bM20K13.3 (tumor necrosis factor (ligand) superfamily, member 15)
    tumor necrosis factor ligand 1b
    vascular endothelial cell growth inhibitor
    vascular endothelial growth inhibitor

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177371.3NP_796345.3  tumor necrosis factor ligand superfamily member 15

      Status: VALIDATED

      Source sequence(s)
      AK041971, AL691468, AY764130
      Consensus CDS
      CCDS18263.2
      UniProtKB/Swiss-Prot
      Q5UBV8
      UniProtKB/TrEMBL
      F6VXB8
      Related
      ENSMUSP00000050144, OTTMUSP00000000344, ENSMUST00000062246, OTTMUST00000000776
      Conserved Domains (1) summary
      cd00184
      Location:114268
      TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      63724603..63745113 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)