Display Settings:

Format

Send to:

Choose Destination
    • Showing Current items.

    Dnah5 dynein, axonemal, heavy chain 5 [ Mus musculus (house mouse) ]

    Gene ID: 110082, updated on 1-Sep-2015
    Official Symbol
    Dnah5provided by MGI
    Official Full Name
    dynein, axonemal, heavy chain 5provided by MGI
    Primary source
    MGI:MGI:107718
    See related
    Ensembl:ENSMUSG00000022262; Vega:OTTMUSG00000026038
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Dnahc5; Mdnah5; AU022615; b2b601Clo; mKIAA1603; b2b1134Clo; b2b1154Clo; b2b1537Clo; b2b1565Clo
    Orthologs
    See Dnah5 in Epigenomics, MapViewer
    Location:
    15 B1; 15 10.9 cM
    Exon count:
    80
    Annotation release Status Assembly Chr Location
    105 current GRCm38.p3 (GCF_000001635.23) 15 NC_000081.6 (28154854..28472045)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (28133521..28401800)

    Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 31458 Neighboring gene ribosomal protein L35 pseudogene Neighboring gene deleted in bladder cancer 1 pseudogene Neighboring gene predicted gene, 31687

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Huntington's disease, organism-specific biosystem (from KEGG)
      Huntington's disease, organism-specific biosystemHuntington disease (HD) is an autosomal-dominant neurodegenerative disorder that primarily affects medium spiny striatal neurons (MSN). The symptoms are choreiform, involuntary movements, personality...
    • Huntington's disease, conserved biosystem (from KEGG)
      Huntington's disease, conserved biosystemHuntington disease (HD) is an autosomal-dominant neurodegenerative disorder that primarily affects medium spiny striatal neurons (MSN). The symptoms are choreiform, involuntary movements, personality...

    Markers

    Homology

    Clone Names

    • KIAA1603

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    ATPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule motor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    motor activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    cilium movement IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cilium movement ISO
    Inferred from Sequence Orthology
    more info
     
    determination of left/right symmetry ISO
    Inferred from Sequence Orthology
    more info
     
    lateral ventricle development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    left/right axis specification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    microtubule-based movement IEA
    Inferred from Electronic Annotation
    more info
     
    outer dynein arm assembly ISO
    Inferred from Sequence Orthology
    more info
     
    sperm motility ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    axonemal dynein complex IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    axoneme IDA
    Inferred from Direct Assay
    more info
    PubMed 
    axoneme ISO
    Inferred from Sequence Orthology
    more info
     
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    cilium IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    dynein complex IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    outer dynein arm ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    dynein heavy chain 5, axonemal
    Names
    axonemal beta dynein heavy chain 5
    axonemal dynein heavy chain 5
    ciliary dynein heavy chain 5
    dynein, axon, heavy chain 5

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133365.3NP_579943.3  dynein heavy chain 5, axonemal

      See identical proteins and their annotated locations for NP_579943.3

      Status: VALIDATED

      Source sequence(s)
      AC131997, AC154880
      Consensus CDS
      CCDS27404.1
      UniProtKB/Swiss-Prot
      Q8VHE6
      Related
      ENSMUSP00000069751, OTTMUSP00000031890, ENSMUST00000067048, OTTMUST00000064272
      Conserved Domains (6) summary
      pfam12777
      Location:31993543
      MT; Microtubule-binding stalk of dynein motor
      pfam12781
      Location:35633792
      AAA_9; ATP-binding dynein motor region D5
      pfam03028
      Location:39294619
      Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
      pfam08385
      Location:246804
      DHC_N1; Dynein heavy chain, N-terminal region 1
      pfam08393
      Location:14011809
      DHC_N2; Dynein heavy chain, N-terminal region 2
      cl21455
      Location:19392170
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p3 C57BL/6J

    Genomic

    1. NC_000081.6 Reference GRCm38.p3 C57BL/6J

      Range
      28154854..28472045
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006520014.2XP_006520077.1  

      Conserved Domains (6) summary
      pfam12777
      Location:31843528
      MT; Microtubule-binding stalk of dynein motor
      pfam12781
      Location:35483777
      AAA_9; ATP-binding dynein motor region D5
      pfam03028
      Location:39144604
      Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
      pfam08385
      Location:231789
      DHC_N1; Dynein heavy chain, N-terminal region 1
      pfam08393
      Location:13861794
      DHC_N2; Dynein heavy chain, N-terminal region 2
      cl21455
      Location:19242155
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    2. XM_006520015.2XP_006520078.1  

      Conserved Domains (5) summary
      pfam12777
      Location:23942738
      MT; Microtubule-binding stalk of dynein motor
      pfam12781
      Location:27582987
      AAA_9; ATP-binding dynein motor region D5
      pfam03028
      Location:31243814
      Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
      pfam08393
      Location:5961004
      DHC_N2; Dynein heavy chain, N-terminal region 2
      cl21455
      Location:11341365
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    Alternate Mm_Celera

    Genomic

    1. AC_000037.1 Alternate Mm_Celera

      Range
      28952222..29215703
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)