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Ahr aryl-hydrocarbon receptor [ Mus musculus (house mouse) ]

Gene ID: 11622, updated on 22-Mar-2015
Official Symbol
Ahrprovided by MGI
Official Full Name
aryl-hydrocarbon receptorprovided by MGI
Primary source
MGI:MGI:105043
See related
Ensembl:ENSMUSG00000019256; Vega:OTTMUSG00000036999
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ah; In; Ahh; Ahre; bHLHe76
Orthologs
See Ahr in MapViewer
Location:
12 A3; 12 15.78 cM
Exon count:
11
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 12 NC_000078.6 (35497979..35534989, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (36182651..36219661, complement)

Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene sorting nexin 13 Neighboring gene microRNA 680-3 Neighboring gene RIKEN cDNA 9130015A21 gene Neighboring gene uncharacterized LOC105244854

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Adipogenesis, organism-specific biosystem (from WikiPathways)
    Adipogenesis, organism-specific biosystemThe different classes of factors involved in adipogenesis are shown. Adipogenesis is the process by which fat cells differentiate from predadipocytes to adipocytes (fat cells). Adipose tissue, compos...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
DNA binding ISO
Inferred from Sequence Orthology
more info
 
E-box binding IDA
Inferred from Direct Assay
more info
PubMed 
Hsp90 protein binding ISO
Inferred from Sequence Orthology
more info
 
Hsp90 protein binding TAS
Traceable Author Statement
more info
PubMed 
RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
aryl hydrocarbon receptor activity ISO
Inferred from Sequence Orthology
more info
 
enhancer binding ISO
Inferred from Sequence Orthology
more info
PubMed 
ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 
protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
sequence-specific DNA binding transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
sequence-specific DNA binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
PubMed 
sequence-specific DNA binding transcription factor activity TAS
Traceable Author Statement
more info
PubMed 
signal transducer activity IEA
Inferred from Electronic Annotation
more info
 
transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
transcription regulatory region DNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
B cell differentiation TAS
Traceable Author Statement
more info
PubMed 
B cell homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
B cell homeostasis TAS
Traceable Author Statement
more info
PubMed 
B-1 B cell homeostasis TAS
Traceable Author Statement
more info
PubMed 
T cell homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
blood circulation IMP
Inferred from Mutant Phenotype
more info
PubMed 
blood vessel development IMP
Inferred from Mutant Phenotype
more info
PubMed 
blood vessel morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
blood vessel remodeling IMP
Inferred from Mutant Phenotype
more info
PubMed 
camera-type eye development IMP
Inferred from Mutant Phenotype
more info
PubMed 
cardiac left ventricle morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cell morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to cAMP IDA
Inferred from Direct Assay
more info
PubMed 
circadian regulation of gene expression IDA
Inferred from Direct Assay
more info
PubMed 
circumferential growth involved in left ventricle morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
common bile duct development IMP
Inferred from Mutant Phenotype
more info
PubMed 
embryonic hemopoiesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
gland development IMP
Inferred from Mutant Phenotype
more info
PubMed 
glomerulus morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
immune system process IMP
Inferred from Mutant Phenotype
more info
PubMed 
intracellular receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
intracellular receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
kidney morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
liver development IMP
Inferred from Mutant Phenotype
more info
PubMed 
lymphocyte homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
lymphocyte homeostasis TAS
Traceable Author Statement
more info
PubMed 
negative regulation of necrotic cell death IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of systemic arterial blood pressure IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription from RNA polymerase II promoter IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of vasoconstriction IMP
Inferred from Mutant Phenotype
more info
PubMed 
ovarian follicle development ISO
Inferred from Sequence Orthology
more info
 
patterning of blood vessels IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of cell size IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
post-embryonic hemopoiesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
prostate gland development IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of B cell proliferation ISO
Inferred from Sequence Orthology
more info
 
regulation of blood pressure TAS
Traceable Author Statement
more info
PubMed 
regulation of blood vessel size IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
regulation of heart growth TAS
Traceable Author Statement
more info
PubMed 
regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription, DNA-templated TAS
Traceable Author Statement
more info
PubMed 
reproductive structure development IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to organic cyclic compound ISO
Inferred from Sequence Orthology
more info
 
response to stress IDA
Inferred from Direct Assay
more info
PubMed 
response to toxic substance IDA
Inferred from Direct Assay
more info
PubMed 
response to toxic substance ISO
Inferred from Sequence Orthology
more info
 
response to xenobiotic stimulus IDA
Inferred from Direct Assay
more info
PubMed 
response to xenobiotic stimulus ISO
Inferred from Sequence Orthology
more info
 
rhythmic process IEA
Inferred from Electronic Annotation
more info
 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
smooth muscle tissue development IMP
Inferred from Mutant Phenotype
more info
PubMed 
spleen development IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription from RNA polymerase II promoter IDA
Inferred from Direct Assay
more info
PubMed 
transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
venous blood vessel development IMP
Inferred from Mutant Phenotype
more info
PubMed 
xenobiotic metabolic process TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
aryl hydrocarbon receptor complex TAS
Traceable Author Statement
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
cytosol ISO
Inferred from Sequence Orthology
more info
 
cytosolic aryl hydrocarbon receptor complex TAS
Traceable Author Statement
more info
PubMed 
nuclear aryl hydrocarbon receptor complex TAS
Traceable Author Statement
more info
PubMed 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
transcription factor complex TAS
Traceable Author Statement
more info
PubMed 
Preferred Names
aryl hydrocarbon receptor
Names
aryl hydrocarbon receptor
ah receptor
dioxin receptor

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013464.4NP_038492.1  aryl hydrocarbon receptor

    See proteins identical to NP_038492.1

    Status: PROVISIONAL

    Source sequence(s)
    AK153678
    Consensus CDS
    CCDS36434.1
    UniProtKB/Swiss-Prot
    P30561
    UniProtKB/TrEMBL
    Q3U5D9
    Related
    ENSMUSP00000112137, OTTMUSP00000053052, ENSMUST00000116436, OTTMUST00000095140
    Conserved Domains (4) summary
    cd00083
    Location:3677
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cd00130
    Location:120177
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam00989
    Location:111177
    PAS; PAS fold
    pfam08447
    Location:291376
    PAS_3; PAS fold

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000078.6 Reference GRCm38.p3 C57BL/6J

    Range
    35497979..35534989
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000034.1 Alternate Mm_Celera

    Range
    36948584..36984257
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)