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Cacybp calcyclin binding protein [ Mus musculus (house mouse) ]

Gene ID: 12301, updated on 5-Apr-2015
Official Symbol
Cacybpprovided by MGI
Official Full Name
calcyclin binding proteinprovided by MGI
Primary source
MGI:MGI:1270839
See related
Ensembl:ENSMUSG00000014226; Vega:OTTMUSG00000050680
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
SIP
Orthologs
See Cacybp in MapViewer
Location:
1; 1 H1
Exon count:
6
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 1 NC_000067.6 (160202367..160212892, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (162133052..162142908, complement)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene tenascin N Neighboring gene mitochondrial ribosomal protein S14 Neighboring gene RAB GTPase activating protein 1-like Neighboring gene microRNA 1927 Neighboring gene G protein-coupled receptor 52

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Wnt signaling pathway, organism-specific biosystem (from KEGG)
    Wnt signaling pathway, organism-specific biosystemWnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, i...
  • Wnt signaling pathway, conserved biosystem (from KEGG)
    Wnt signaling pathway, conserved biosystemWnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, i...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
cardiac muscle cell differentiation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of cell death ISO
Inferred from Sequence Orthology
more info
 
positive regulation of DNA replication ISO
Inferred from Sequence Orthology
more info
 
response to growth hormone ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
beta-catenin destruction complex ISO
Inferred from Sequence Orthology
more info
 
cell body ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
neuron projection ISO
Inferred from Sequence Orthology
more info
 
nuclear envelope lumen IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
calcyclin-binding protein
Names
calcyclin-binding protein
siah-interacting protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009786.2NP_033916.1  calcyclin-binding protein

    See identical proteins and their annotated locations for NP_033916.1

    Status: VALIDATED

    Source sequence(s)
    AC154873, AK013924
    Consensus CDS
    CCDS15406.1
    UniProtKB/Swiss-Prot
    Q9CXW3
    Related
    ENSMUSP00000014370, OTTMUSP00000069117, ENSMUST00000014370, OTTMUST00000128481
    Conserved Domains (3) summary
    cd06468
    Location:76168
    p23_CacyBP; p23_like domain found in proteins similar to Calcyclin-Binding Protein(CacyBP)/Siah-1-interacting protein (SIP). CacyBP/SIP interacts with S100A6 (calcyclin), with some other members of the S100 family, with tubulin, and with Siah-1 and Skp-1. The latter ...
    pfam09032
    Location:176
    Siah-Interact_N; Siah interacting protein, N terminal
    pfam05002
    Location:164219
    SGS; SGS domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000067.6 Reference GRCm38.p3 C57BL/6J

    Range
    160202367..160212892
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000023.1 Alternate Mm_Celera

    Range
    162614123..162624653
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)