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GCN4 amino acid starvation-responsive transcription factor GCN4 [ Saccharomyces cerevisiae S288c ]

Gene ID: 856709, updated on 22-Feb-2015
Gene symbol
GCN4
Gene description
amino acid starvation-responsive transcription factor GCN4
Primary source
SGD:S000000735
Locus tag
YEL009C
Gene type
protein coding
RNA name
amino acid starvation-responsive transcription factor GCN4
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
AAS101; AAS3; ARG9
See GCN4 in MapViewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (138918..139763, complement)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene tRNA Neighboring gene tRNA Neighboring gene Mit1p Neighboring gene Yea6p

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription IPI
Inferred from Physical Interaction
more info
PubMed 
RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription IDA
Inferred from Direct Assay
more info
PubMed 
RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription IMP
Inferred from Mutant Phenotype
more info
PubMed 
RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription IPI
Inferred from Physical Interaction
more info
PubMed 
RNA polymerase II transcription factor recruiting transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
RNA polymerase II transcription factor recruiting transcription factor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
RNA polymerase II transcription factor recruiting transcription factor activity IPI
Inferred from Physical Interaction
more info
PubMed 
TFIID-class binding transcription factor activity IPI
Inferred from Physical Interaction
more info
PubMed 
chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
sequence-specific DNA binding transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
sequence-specific DNA binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
sequence-specific DNA binding transcription factor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
cellular amino acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
nitrogen catabolite activation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cellular response to amino acid starvation IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of cellular response to amino acid starvation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription initiation from RNA polymerase II promoter IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of transcription initiation from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
amino acid starvation-responsive transcription factor GCN4
NP_010907.3
  • bZIP transcriptional activator of amino acid biosynthetic genes; activator responds to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    138918..139763
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178824.3NP_010907.3  amino acid starvation-responsive transcription factor GCN4 [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_010907.3

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P03069
    Conserved Domains (2) summary
    cd12192
    Location:106134
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    cd12193
    Location:226279
    B_zip1; basic leucine zipper DNA-binding and multimerization region of GCN4 and related proteins