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    Sftpa1 surfactant associated protein A1 [ Mus musculus (house mouse) ]

    Gene ID: 20387, updated on 27-Aug-2016
    Official Symbol
    Sftpa1provided by MGI
    Official Full Name
    surfactant associated protein A1provided by MGI
    Primary source
    MGI:MGI:109518
    See related
    Ensembl:ENSMUSG00000021789 Vega:OTTMUSG00000035515
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SP-A; Sftp1; Sftp-1
    Location:
    14 B; 14 22.36 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (41131788..41136373)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (41945077..41949662)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene DPY30 domain containing 2 Neighboring gene DPY30 domain containing 1 Neighboring gene methionine adenosyltransferase I, alpha Neighboring gene pleckstrin homology domain containing, family F (with FYVE domain) member 2 pseudogene Neighboring gene mannose-binding lectin (protein A) 1

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • Metabolism of proteins, organism-specific biosystem (from REACTOME)
      Metabolism of proteins, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Pertussis, organism-specific biosystem (from KEGG)
      Pertussis, organism-specific biosystemPertussis, also known as whooping cough, is an acute respiratory infectious disease caused by a bacteria called Bordetella Pertussis. The characteristic symptoms are paroxysmal cough, inspiratory whe...
    • Pertussis, conserved biosystem (from KEGG)
      Pertussis, conserved biosystemPertussis, also known as whooping cough, is an acute respiratory infectious disease caused by a bacteria called Bordetella Pertussis. The characteristic symptoms are paroxysmal cough, inspiratory whe...
    • Phagosome, organism-specific biosystem (from KEGG)
      Phagosome, organism-specific biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
    • Phagosome, conserved biosystem (from KEGG)
      Phagosome, conserved biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
    • Surfactant metabolism, organism-specific biosystem (from REACTOME)
      Surfactant metabolism, organism-specific biosystemcomputationally inferred pathway (not manually curated)

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    positive regulation of phagocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasmic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    multivesicular body ISO
    Inferred from Sequence Orthology
    more info
     
    rough endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    pulmonary surfactant-associated protein A
    Names
    PSAP
    PSP-A
    surfactant pulmonary associated protein A1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023134.4NP_075623.2  pulmonary surfactant-associated protein A precursor

      See identical proteins and their annotated locations for NP_075623.2

      Status: PROVISIONAL

      Source sequence(s)
      AK004788
      Consensus CDS
      CCDS26960.1
      UniProtKB/TrEMBL
      Q9CQI1
      Related
      ENSMUSP00000129696, OTTMUSP00000050032, ENSMUST00000170719, OTTMUST00000090957
      Conserved Domains (2) summary
      cd03591
      Location:136248
      CLECT_collectin_like; C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1)
      pfam01391
      Location:2798
      Collagen; Collagen triple helix repeat (20 copies)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

      Range
      41131788..41136373
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)