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    Pde6b phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide [ Mus musculus (house mouse) ]

    Gene ID: 18587, updated on 4-Jul-2015
    Official Symbol
    Pde6bprovided by MGI
    Official Full Name
    phosphodiesterase 6B, cGMP, rod receptor, beta polypeptideprovided by MGI
    Primary source
    MGI:MGI:97525
    See related
    Ensembl:ENSMUSG00000029491; Vega:OTTMUSG00000026326
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    r; rd; rd1; Pdeb; rd-1; rd10
    Orthologs
    See Pde6b in Epigenomics, MapViewer
    Location:
    5 F; 5 53.07 cM
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    105 current GRCm38.p3 (GCF_000001635.23) 5 NC_000071.6 (108388373..108431743)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (108817392..108860762)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105246958 Neighboring gene predicted gene 10419 Neighboring gene predicted gene, 34254 Neighboring gene predicted gene, 34204 Neighboring gene predicted gene, 34319 Neighboring gene ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit E Neighboring gene major facilitator superfamily domain containing 7A

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Markers

    Homology

    Clone Names

    • MGC150321

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    3',5'-cyclic-GMP phosphodiesterase activity ISO
    Inferred from Sequence Orthology
    more info
     
    3',5'-cyclic-nucleotide phosphodiesterase activity IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    phosphoric diester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    GMP metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    cytosolic calcium ion homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    detection of light stimulus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    retina development in camera-type eye IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    visual perception IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    photoreceptor outer segment IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
    Names
    GMP-PDE beta
    cGMP-phosphodiesterase beta-subunit
    phosphodiesterase, cGMP, rod receptor, beta polypeptide
    retinal degeneration 1
    NP_032832.2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008806.2NP_032832.2  rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta precursor

      See identical proteins and their annotated locations for NP_032832.2

      Status: VALIDATED

      Source sequence(s)
      AK044364, BE944318, BU505563
      Consensus CDS
      CCDS19510.1
      UniProtKB/Swiss-Prot
      P23440
      Related
      ENSMUSP00000031456, OTTMUSP00000032409, ENSMUST00000031456, OTTMUST00000065111
      Conserved Domains (2) summary
      smart00065
      Location:71230
      GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
      cd00077
      Location:556741
      HDc; Metal dependent phosphohydrolases with conserved 'HD' motif

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p3 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p3 C57BL/6J

      Range
      108388373..108431743
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Mm_Celera

    Genomic

    1. AC_000027.1 Alternate Mm_Celera

      Range
      105508147..105551677
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)