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Tff2 trefoil factor 2 (spasmolytic protein 1) [ Mus musculus (house mouse) ]

Gene ID: 21785, updated on 8-Jul-2014
Official Symbol
Tff2provided by MGI
Official Full Name
trefoil factor 2 (spasmolytic protein 1)provided by MGI
Primary source
MGI:1306805
See related
Ensembl:ENSMUSG00000024028; Vega:OTTMUSG00000020098
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
SP; mSP
See Tff2 in Epigenomics, MapViewer
Location:
17 A3.3; 17 15.8 cM
Exon count :
4
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 17 NC_000083.6 (31141062..31144282, complement)

Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene ATP-binding cassette, sub-family G (WHITE), member 1 Neighboring gene trefoil factor 3, intestinal Neighboring gene uncharacterized LOC102631757 Neighboring gene trefoil factor 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
CXCR4 chemokine receptor binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
calcium-mediated signaling IDA
Inferred from Direct Assay
more info
PubMed 
chemokine-mediated signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of gastric acid secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of inflammatory response IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of macrophage activation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of ERK1 and ERK2 cascade IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of cell proliferation IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cell migration IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
intracellular IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
trefoil factor 2
Names
trefoil factor 2
spasmolytic polypeptide

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009363.3NP_033389.2  trefoil factor 2 precursor

    See proteins identical to NP_033389.2

    Status: PROVISIONAL

    Source sequence(s)
    AK003093
    Consensus CDS
    CCDS37545.1
    UniProtKB/TrEMBL
    Q9QX97
    Related
    ENSMUSP00000024826, OTTMUSP00000021728, ENSMUST00000024826, OTTMUST00000047794
    Conserved Domains (1) summary
    cd00111
    Location:79121
    Blast Score: 141
    Trefoil; P or trefoil or TFF domain; Trefoil factor family domain peptides are mucin-associated molecules, largely found in epithelia of gastrointestinal tissues. Function is not known but it was originally identified from mucosal tissues, where it may have a ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000083.6 

    Range
    31141062..31144282
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000039.1 

    Range
    32058241..32061428
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Supplemental Content

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