Display Settings:

Format

Send to:

Choose Destination

Lhcgr luteinizing hormone/choriogonadotropin receptor [ Mus musculus (house mouse) ]

Gene ID: 16867, updated on 11-Sep-2014
Official Symbol
Lhcgrprovided by MGI
Official Full Name
luteinizing hormone/choriogonadotropin receptorprovided by MGI
Primary source
MGI:96783
See related
Ensembl:ENSMUSG00000024107
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Lhr; LH-R; Gpcr19-rs1
See Lhcgr in Epigenomics, MapViewer
Location:
17 E4-E5; 17 58.35 cM
Exon count:
12
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 17 NC_000083.6 (88741132..88792059, complement)

Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102634168 Neighboring gene uncharacterized LOC102634281 Neighboring gene general transcription factor IIA, 1-like Neighboring gene predicted gene 9407 Neighboring gene MARCKS-like 1, pseudogene 2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATPase binding ISO
Inferred from Sequence Orthology
more info
 
G-protein coupled peptide receptor activity ISO
Inferred from Sequence Orthology
more info
 
G-protein coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
choriogonadotropin hormone binding IDA
Inferred from Direct Assay
more info
PubMed 
choriogonadotropin hormone receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
choriogonadotropin hormone receptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
luteinizing hormone receptor activity TAS
Traceable Author Statement
more info
PubMed 
peptide hormone binding ISO
Inferred from Sequence Orthology
more info
 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
protein-hormone receptor activity IEA
Inferred from Electronic Annotation
more info
 
signal transducer activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
activation of adenylate cyclase activity IDA
Inferred from Direct Assay
more info
PubMed 
activation of adenylate cyclase activity ISO
Inferred from Sequence Orthology
more info
 
adenylate cyclase-modulating G-protein coupled receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
arachidonic acid secretion ISO
Inferred from Sequence Orthology
more info
 
cellular response to gonadotropin stimulus IDA
Inferred from Direct Assay
more info
PubMed 
cognition ISO
Inferred from Sequence Orthology
more info
 
development of secondary male sexual characteristics IMP
Inferred from Mutant Phenotype
more info
PubMed 
female gonad development IMP
Inferred from Mutant Phenotype
more info
PubMed 
hormone-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
luteinizing hormone signaling pathway ISO
Inferred from Sequence Orthology
more info
 
luteinizing hormone signaling pathway TAS
Traceable Author Statement
more info
PubMed 
male gonad development IMP
Inferred from Mutant Phenotype
more info
PubMed 
ovarian follicle development IMP
Inferred from Mutant Phenotype
more info
PubMed 
ovulation cycle process IMP
Inferred from Mutant Phenotype
more info
PubMed 
phospholipase C-activating G-protein coupled receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
phospholipase C-activating G-protein coupled receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cAMP-mediated signaling IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of calcium ion transport into cytosol ISO
Inferred from Sequence Orthology
more info
 
positive regulation of calcium-mediated signaling ISO
Inferred from Sequence Orthology
more info
 
positive regulation of hormone biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of inositol trisphosphate biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of release of sequestered calcium ion into cytosol ISO
Inferred from Sequence Orthology
more info
 
protein targeting to lysosome ISO
Inferred from Sequence Orthology
more info
 
regulation of steroid hormone biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
seminiferous tubule development IMP
Inferred from Mutant Phenotype
more info
PubMed 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
spermatogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
uterus development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
endosome ISO
Inferred from Sequence Orthology
more info
 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
integral component of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
intrinsic component of external side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
lysosome ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
receptor complex ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
lutropin-choriogonadotropic hormone receptor
Names
lutropin-choriogonadotropic hormone receptor
LSH-R
LH/CG-R
luteinizing hormone receptor

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013582.2NP_038610.1  lutropin-choriogonadotropic hormone receptor precursor

    See proteins identical to NP_038610.1

    Status: PROVISIONAL

    Source sequence(s)
    AC154459
    Consensus CDS
    CCDS29025.1
    UniProtKB/Swiss-Prot
    P30730
    Related
    ENSMUSP00000024916, ENSMUST00000024916
    Conserved Domains (2) summary
    pfam00001
    Location:386627
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam13306
    Location:66204
    LRR_5; Leucine rich repeats (6 copies)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000083.6 

    Range
    88741132..88792059
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006523723.1XP_006523786.1  

    Conserved Domains (1) summary
    pfam00001
    Location:261502
    7tm_1; 7 transmembrane receptor (rhodopsin family)
  2. XM_006523722.1XP_006523785.1  

    Conserved Domains (2) summary
    pfam00001
    Location:312553
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam01295
    Location:105205
    Adenylate_cycl; Adenylate cyclase, class-I
  3. XM_006523720.1XP_006523783.1  

    Conserved Domains (3) summary
    pfam00001
    Location:337578
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam01295
    Location:130230
    Adenylate_cycl; Adenylate cyclase, class-I
    pfam13306
    Location:64163
    LRR_5; Leucine rich repeats (6 copies)
  4. XM_006523719.1XP_006523782.1  

    Conserved Domains (2) summary
    pfam00001
    Location:362603
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam13855
    Location:54115
    LRR_8; Leucine rich repeat
  5. XM_006523721.1XP_006523784.1  

    Conserved Domains (3) summary
    pfam00001
    Location:336577
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam01295
    Location:129229
    Adenylate_cycl; Adenylate cyclase, class-I
    pfam13306
    Location:65162
    LRR_5; Leucine rich repeats (6 copies)
  6. XM_006523724.1XP_006523787.1  

    Conserved Domains (3) summary
    pfam00001
    Location:319483
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam01295
    Location:179279
    Adenylate_cycl; Adenylate cyclase, class-I
    pfam13306
    Location:66204
    LRR_5; Leucine rich repeats (6 copies)
  7. XM_006523725.1XP_006523788.1  

    Conserved Domains (2) summary
    pfam01295
    Location:179279
    Adenylate_cycl; Adenylate cyclase, class-I
    pfam13306
    Location:66204
    LRR_5; Leucine rich repeats (6 copies)
  8. XM_006523726.1XP_006523789.1  

    Conserved Domains (2) summary
    pfam01295
    Location:179279
    Adenylate_cycl; Adenylate cyclase, class-I
    pfam13306
    Location:66204
    LRR_5; Leucine rich repeats (6 copies)
  9. XM_006523727.1XP_006523790.1  

    Conserved Domains (2) summary
    pfam01295
    Location:179279
    Adenylate_cycl; Adenylate cyclase, class-I
    pfam13306
    Location:66204
    LRR_5; Leucine rich repeats (6 copies)

Alternate Mm_Celera

Genomic

  1. AC_000039.1 

    Range
    93149952..93199996
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)